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PCNT and SH3BGR
Data Source:
BioGRID
(affinity chromatography technology)
PCNT
SH3BGR
Description
pericentrin
SH3 domain binding glutamate rich protein
Image
No pdb structure
No pdb structure
GO Annotations
Cellular Component
Centrosome
Centriole
Cytosol
Microtubule
Membrane
Centriolar Satellite
Cytosol
Molecular Function
Protein Binding
Calmodulin Binding
Molecular Adaptor Activity
SH3 Domain Binding
Biological Process
G2/M Transition Of Mitotic Cell Cycle
Microtubule Cytoskeleton Organization
Mitotic Spindle Organization
Signal Transduction
Regulation Of G2/M Transition Of Mitotic Cell Cycle
Cilium Assembly
Positive Regulation Of Intracellular Protein Transport
Ciliary Basal Body-plasma Membrane Docking
Protein-containing Complex Assembly
Pathways
Regulation of PLK1 Activity at G2/M Transition
Loss of Nlp from mitotic centrosomes
Recruitment of mitotic centrosome proteins and complexes
Loss of proteins required for interphase microtubule organization from the centrosome
Recruitment of NuMA to mitotic centrosomes
Anchoring of the basal body to the plasma membrane
AURKA Activation by TPX2
Chaperone Mediated Autophagy
Late endosomal microautophagy
Aggrephagy
Aggrephagy
Drugs
Diseases
Microcephalic osteodysplastic primordial dwarfism, type II (MOPD II)
Seckel syndrome
GWAS
Heel bone mineral density (
30598549
)
Pre-treatment viral load in HIV-1 infection (
31219150
)
Treatment resistant depression (
30468137
)
Interacting Genes
11 interacting genes:
AKAP9
CALM1
CALM2
CCP110
CEP55
DISC1
PCM1
TP53BP1
TUBG1
TUBGCP2
TUBGCP3
2 interacting genes:
CAPN1
FCHSD2
Entrez ID
5116
6450
HPRD ID
05804
03753
Ensembl ID
ENSG00000160299
ENSG00000185437
Uniprot IDs
O95613
C9JJT2
P55822
PDB IDs
Enriched GO Terms of Interacting Partners
?
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Tagcloud (Difference)
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Tagcloud (Intersection)
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