PCNT and NDUFV3

Data Source:
BioGRID (proximity labelling technology)

		PCNT	NDUFV3
Description		pericentrin	NADH:ubiquinone oxidoreductase subunit V3
Image		No pdb structure
GO Annotations	Cellular Component	Centrosome Centriole Cytosol Microtubule Membrane Centriolar Satellite	Mitochondrion Mitochondrial Inner Membrane Mitochondrial Respiratory Chain Complex I
	Molecular Function	Protein Binding Calmodulin Binding Molecular Adaptor Activity	RNA Binding Protein Binding NADH Dehydrogenase (ubiquinone) Activity
	Biological Process	G2/M Transition Of Mitotic Cell Cycle Microtubule Cytoskeleton Organization Mitotic Spindle Organization Signal Transduction Regulation Of G2/M Transition Of Mitotic Cell Cycle Cilium Assembly Positive Regulation Of Intracellular Protein Transport Ciliary Basal Body-plasma Membrane Docking	Mitochondrial Electron Transport, NADH To Ubiquinone Mitochondrial Respiratory Chain Complex I Assembly Mitochondrial ATP Synthesis Coupled Electron Transport
Pathways		Regulation of PLK1 Activity at G2/M Transition Loss of Nlp from mitotic centrosomes Recruitment of mitotic centrosome proteins and complexes Loss of proteins required for interphase microtubule organization from the centrosome Recruitment of NuMA to mitotic centrosomes Anchoring of the basal body to the plasma membrane AURKA Activation by TPX2 Chaperone Mediated Autophagy Late endosomal microautophagy Aggrephagy Aggrephagy	Respiratory electron transport Complex I biogenesis
Drugs			NADH Ubidecarenone
Diseases		Microcephalic osteodysplastic primordial dwarfism, type II (MOPD II) Seckel syndrome
GWAS		Heel bone mineral density ( 30598549) Pre-treatment viral load in HIV-1 infection ( 31219150) Treatment resistant depression ( 30468137)
Interacting Genes		11 interacting genes: AKAP9 CALM1 CALM2 CCP110 CEP55 DISC1 PCM1 TP53BP1 TUBG1 TUBGCP2 TUBGCP3	1 interacting genes: PHYHIP
Entrez ID		5116	4731
HPRD ID		05804	03716
Ensembl ID		ENSG00000160299	ENSG00000160194
Uniprot IDs		O95613	P56181
PDB IDs			5XTB 5XTD 5XTH 5XTI
Enriched GO Terms of Interacting Partners?
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