IFT52 and SPINT3

Data Source:
BioGRID (enzymatic study)

		IFT52	SPINT3
Description		intraflagellar transport 52	serine peptidase inhibitor, Kunitz type 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Centrosome Centriole Cilium Intraciliary Transport Particle B Motile Cilium Photoreceptor Connecting Cilium Ciliary Basal Body Dendrite Terminus Ciliary Tip Ciliary Base	Extracellular Region
	Molecular Function	Protein C-terminus Binding	Serine-type Endopeptidase Inhibitor Activity Receptor Antagonist Activity Transforming Growth Factor Beta Binding
	Biological Process	Neural Tube Formation Heart Looping Smoothened Signaling Pathway Dorsal/ventral Pattern Formation Intraciliary Anterograde Transport Intraciliary Transport Involved In Cilium Assembly Intraciliary Transport Embryonic Digit Morphogenesis Negative Regulation Of Epithelial Cell Proliferation Cilium Assembly Regulation Of Protein Processing Non-motile Cilium Assembly	Negative Regulation Of Endopeptidase Activity Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Negative Regulation Of Signaling Receptor Activity
Pathways		Hedgehog 'off' state Intraflagellar transport Intraflagellar transport
Drugs
Diseases
GWAS		Mean reticulocyte volume ( 32888494)	Blood protein levels ( 30072576 29875488) Brain structure ( 20171287)
Interacting Genes
Entrez ID		51098	10816
HPRD ID		12789	19468
Ensembl ID		ENSG00000101052	ENSG00000101446
Uniprot IDs		Q9Y366	P49223
PDB IDs
Enriched GO Terms of Interacting Partners?
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