MRPS7 and ASXL1

Data Source:
BioGRID (affinity chromatography technology)

		MRPS7	ASXL1
Description		mitochondrial ribosomal protein S7	ASXL transcriptional regulator 1
Image			No pdb structure
GO Annotations	Cellular Component	Mitochondrial Inner Membrane Mitochondrial Small Ribosomal Subunit Ribosome	Nucleoplasm PR-DUB Complex
	Molecular Function	RNA Binding MRNA Binding Structural Constituent Of Ribosome RRNA Binding	DNA Binding Chromatin Binding Transcription Coactivator Activity Protein Binding Retinoic Acid Receptor Binding Peroxisome Proliferator Activated Receptor Binding Metal Ion Binding
	Biological Process	Ribosomal Small Subunit Assembly Translation Mitochondrial Translation Mitochondrial Translational Elongation Mitochondrial Translational Termination	Cell Morphogenesis Heart Morphogenesis Transcription, DNA-templated Animal Organ Morphogenesis Negative Regulation Of Lipid Storage Protein Deubiquitination Hemopoiesis Response To Retinoic Acid Negative Regulation Of Peroxisome Proliferator Activated Receptor Signaling Pathway Monoubiquitinated Histone H2A Deubiquitination Regulation Of Kidney Size Negative Regulation Of Fat Cell Differentiation Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Retinoic Acid Receptor Signaling Pathway Thymus Development Bone Marrow Development Homeostasis Of Number Of Cells Lung Saccule Development Glomerular Visceral Epithelial Cell Development
Pathways		Mitochondrial translation initiation Mitochondrial translation elongation Mitochondrial translation elongation Mitochondrial translation termination	UCH proteinases
Drugs
Diseases			C syndrome, including: Opitz trigonocephaly syndrome; Bohring-Opitz syndrome (BOPS)
GWAS			Chronic obstructive pulmonary disease or high blood pressure (pleiotropy) ( 30940143) Inflammatory bowel disease ( 28067908) Red cell distribution width ( 32888494)
Interacting Genes		1 interacting genes: PTEN	6 interacting genes: APP GOLGA6L9 H1-2 SRPK1 STAT3 UBC
Entrez ID		51081	171023
HPRD ID		17601	16516
Ensembl ID		ENSG00000125445	ENSG00000171456
Uniprot IDs		A0A024R8L0 Q9Y2R9	Q498B9 Q8IXJ9
PDB IDs		3J9M 6NU2 6NU3 6RW4 6RW5 6VLZ 6VMI 6ZS9 6ZSA 6ZSB 6ZSC 6ZSD 6ZSE 6ZSG
Enriched GO Terms of Interacting Partners?
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