PCDH7 and BST1

Data Source:
BioGRID (affinity chromatography technology)

		PCDH7	BST1
Description		protocadherin 7	bone marrow stromal cell antigen 1
Image
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Platelet Alpha Granule Membrane	Uropod Extracellular Region Plasma Membrane Extrinsic Component Of Membrane Anchored Component Of Membrane Specific Granule Membrane Extracellular Exosome
	Molecular Function	Calcium Ion Binding	NAD+ Nucleosidase Activity Transferase Activity Phosphorus-oxygen Lyase Activity NAD(P)+ Nucleosidase Activity NAD+ Nucleotidase, Cyclic ADP-ribose Generating ADP-ribosyl Cyclase Activity Cyclic ADP-ribose Hydrolase
	Biological Process	Platelet Degranulation Cell Adhesion Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules	Regulation Of Cell-matrix Adhesion Regulation Of Cellular Extravasation Humoral Immune Response Signal Transduction Positive Regulation Of Cell Population Proliferation NAD Metabolic Process Positive Regulation Of B Cell Proliferation Regulation Of Actin Cytoskeleton Organization Neutrophil Degranulation Regulation Of Inflammatory Response Regulation Of Peptidyl-tyrosine Phosphorylation Regulation Of Calcium-mediated Signaling Regulation Of Neutrophil Chemotaxis Regulation Of Superoxide Metabolic Process Regulation Of Integrin-mediated Signaling Pathway
Pathways		Platelet degranulation	Post-translational modification: synthesis of GPI-anchored proteins Nicotinate metabolism Neutrophil degranulation
Drugs			Etheno-NAD Nicotinamide Adenosine 5'-[gamma-thio]triphosphate Nicotinamide Mononucleotide Etheno-Nadp
Diseases
GWAS		Adult body size ( 32376654) Adventurousness ( 30643258) Alzheimer's disease (late onset) ( 30820047) Attention deficit hyperactivity disorder ( 32279069) Body size at age 10 ( 32376654) Depressive symptom (sleep problems) (binary trait) ( 31530331) Diastolic blood pressure x smoking status (ever vs never) interaction (1df test) ( 29455858) Diastolic blood pressure x smoking status (ever vs never) interaction (2df test) ( 29455858) Diffusing capacity of carbon monoxide ( 30694715) Electroencephalogram traits ( 25387704) Epilepsy ( 25087078) General risk tolerance (MTAG) ( 30643258) Generalized epilepsy ( 30531953) Hip circumference adjusted for BMI ( 28552196) Influenza A (H1N1) infection ( 26379185) Lipid traits ( 22028671) Mean arterial pressure x educational attainment (some college) interaction (2df) ( 32372009) Menarche (age at onset) ( 25231870) Mild influenza (H1N1) infection ( 26379185) Mouth morphology (principal component model) ( 30174134) Number of sexual partners ( 30643258) Obesity-related traits ( 23251661) Refractive astigmatism ( 25367360) Refractive error ( 32231278) Response to antipsychotic treatment in schizophrenia ( 29503163) Response to ziprazidone in schizophrenia ( 29503163) Smoking status (ever vs never smokers) ( 30643258) Underweight status ( 25133637) Very long-chain saturated fatty acid levels (fatty acid 22:0) ( 25378659) White matter hyperintensities in ischemic stroke ( 26674333)	Blood protein levels ( 30072576 29875488 28240269) Current cigarettes per day in chronic obstructive pulmonary disease ( 21685187) Parkinson's disease ( 22451204 21084426 21292315 19915576 25064009 32201043 27182965 32310270) Parkinson's disease or first degree relation to individual with Parkinson's disease ( 31701892) Response to beta blocker use in hypertension (systolic blood pressure) ( 31423876) Urinary metabolite levels in chronic kidney disease ( 31959995)
Interacting Genes		2 interacting genes: MTDH PPP1CA	2 interacting genes: CAV1 LBP
Entrez ID		5099	683
HPRD ID		04288	02665
Ensembl ID		ENSG00000169851	ENSG00000109743
Uniprot IDs		O60245	Q10588
PDB IDs		2YST	1ISF 1ISG 1ISH 1ISI 1ISJ 1ISM
Enriched GO Terms of Interacting Partners?
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