PDE11A and AGPS

Data Source:
BioGRID (proximity labelling technology)

		PDE11A	AGPS
Description		phosphodiesterase 11A	alkylglycerone phosphate synthase
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cellular_component Cytosol	Nucleolus Mitochondrion Peroxisome Peroxisomal Membrane Peroxisomal Matrix Cytosol Membrane
	Molecular Function	Cyclic-nucleotide Phosphodiesterase Activity 3',5'-cyclic-nucleotide Phosphodiesterase Activity 3',5'-cyclic-AMP Phosphodiesterase Activity CGMP-stimulated Cyclic-nucleotide Phosphodiesterase Activity CGMP Binding Metal Ion Binding 3',5'-cyclic-GMP Phosphodiesterase Activity	Protein Binding Alkylglycerone-phosphate Synthase Activity Oxidoreductase Activity FAD Binding
	Biological Process	Signal Transduction G Protein-coupled Receptor Signaling Pathway Metabolic Process Negative Regulation Of CGMP-mediated Signaling Negative Regulation Of CAMP-mediated Signaling	Protein Targeting To Peroxisome Lipid Biosynthetic Process Ether Lipid Biosynthetic Process
Pathways		cGMP effects G alpha (s) signalling events	Plasmalogen biosynthesis Peroxisomal protein import Peroxisomal protein import TYSND1 cleaves peroxisomal proteins
Drugs		Caffeine Tadalafil Trapidil
Diseases		Pigmented micronodular adrenocortical disease (PPNAD)	Rhizomelic chondrodysplasia punctata, including: Rhizomelic chondrodysplasia punctata, type I (RCDP1); Rhizomelic chondrodysplasia punctata, type II (RCDP2); Rhizomelic chondrodysplasia punctata, type III (RCDP3)
GWAS		Cough in response to angiotensin-converting enzyme inhibitor drugs ( 28084903) Diastolic blood pressure ( 29212154) Diffusing capacity of carbon monoxide ( 30694715) Heart rate ( 23583979) Height ( 28552196 20881960) High myopia ( 31816047) Myopia ( 27182965) Refractive error ( 32231278) Spherical equivalent or myopia (age of diagnosis) ( 29808027) Systolic blood pressure ( 30224653)	Height ( 28552196)
Interacting Genes			2 interacting genes: GNPAT GORASP1
Entrez ID		50940	8540
HPRD ID		05391	04337
Ensembl ID		ENSG00000128655	ENSG00000018510
Uniprot IDs		Q9HCR9	B7Z3Q4 O00116
PDB IDs
Enriched GO Terms of Interacting Partners?
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