SMARCAL1 and ACSL3

Data Source:
BioGRID (affinity chromatography technology)

		SMARCAL1	ACSL3
Description		SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a like 1	acyl-CoA synthetase long chain family member 3
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm DNA Replication Factor A Complex Site Of Double-strand Break Nuclear Replication Fork	Mitochondrial Outer Membrane Peroxisomal Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Golgi Apparatus Lipid Droplet Plasma Membrane Membrane Integral Component Of Membrane Perinuclear Region Of Cytoplasm
	Molecular Function	Protein Binding ATP Binding DNA-dependent ATPase Activity Annealing Helicase Activity	Long-chain Fatty Acid-CoA Ligase Activity Protein Binding ATP Binding Protein Kinase Binding Protein Domain Specific Binding Arachidonate-CoA Ligase Activity
	Biological Process	DNA Strand Renaturation DNA Metabolic Process DNA Repair Double-strand Break Repair Via Nonhomologous End Joining Regulation Of Transcription By RNA Polymerase II Cellular Response To DNA Damage Stimulus Replication Fork Processing DNA Duplex Unwinding Replication Fork Protection T-circle Formation	Long-chain Fatty Acid Metabolic Process Fatty Acid Biosynthetic Process Brain Development Response To Nutrient Response To Organic Cyclic Compound Neuron Differentiation Very-low-density Lipoprotein Particle Assembly Long-chain Fatty-acyl-CoA Metabolic Process Long-chain Fatty-acyl-CoA Biosynthetic Process Positive Regulation Of Golgi To Plasma Membrane Protein Transport Long-chain Fatty Acid Import Into Cell Positive Regulation Of Secretion Positive Regulation Of Phosphatidylcholine Biosynthetic Process
Pathways			Intracellular metabolism of fatty acids regulates insulin secretion Synthesis of very long-chain fatty acyl-CoAs
Drugs
Diseases		Schimke immunoosseous dysplasia
GWAS		Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical thickness (MOSTest) ( 32665545) Extremely high intelligence ( 29520040) HDL cholesterol levels x short total sleep time interaction (2df test) ( 31719535) Response to anti-TNF therapy in rheumatoid arthritis ( 26776603) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545) White matter integrity (fractional anisotropy) ( 32358547)	Mild influenza (H1N1) infection ( 26379185)
Interacting Genes			2 interacting genes: APP NDRG1
Entrez ID		50485	2181
HPRD ID		05969	03845
Ensembl ID		ENSG00000138375	ENSG00000123983
Uniprot IDs		Q9NZC9	A0A024R487 O95573
PDB IDs		4MQV
Enriched GO Terms of Interacting Partners?
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