SIX6 and TMEM33

Data Source:
BioGRID (affinity chromatography technology)

		SIX6	TMEM33
Description		SIX homeobox 6	transmembrane protein 33
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Transcription Regulator Complex	Nuclear Envelope Endoplasmic Reticulum Endoplasmic Reticulum Membrane Integral Component Of Endoplasmic Reticulum Membrane Melanosome
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Sequence-specific Double-stranded DNA Binding	Protein Binding
	Biological Process	Eye Development Regulation Of Transcription By RNA Polymerase II Visual Perception Animal Organ Morphogenesis	Response To Endoplasmic Reticulum Stress Membrane Organization Endoplasmic Reticulum Tubular Network Organization Regulation Of Endoplasmic Reticulum Tubular Network Organization Positive Regulation Of IRE1-mediated Unfolded Protein Response Positive Regulation Of PERK-mediated Unfolded Protein Response
Pathways
Drugs
Diseases		Anophthalmia and microphthalmia (A/M)
GWAS		Exhaled carbon monoxide levels in smokers with chronic obstructive pulmonary disease ( 29631575) Glaucoma ( 30054594) Glaucoma (primary open-angle) ( 22419738 29891935 25173105 29452408 22570617) Gut microbiota (bacterial taxa) ( 27723756) Height ( 20881960 25429064) Medication use (antiglaucoma preparations and miotics) ( 31015401) Menarche (age at onset) ( 25231870) Optic cup area ( 25631615 31798171 28073927) Optic disc area ( 25631615 31798171 28073927) Refractive error ( 23396134 32231278) Spherical equivalent (joint analysis main effects and education interaction) ( 27020472) Urinary sodium excretion ( 31409800) Vertical cup-disc ratio ( 31798171 25241763 28073927)	Helping behaviour (self reported) ( 29324852) Neurociticism ( 29500382)
Interacting Genes		3 interacting genes: GTF2A1L TLE1 TLE5	3 interacting genes: MTNR1A RPS14 SLC29A2
Entrez ID		4990	55161
HPRD ID		07557	07680
Ensembl ID		ENSG00000184302	ENSG00000109133
Uniprot IDs		O95475 Q6P051	A0A024R9W7 P57088
PDB IDs
Enriched GO Terms of Interacting Partners?
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