NMB and KIF23

Data Source:
BioGRID (two hybrid)

		NMB	KIF23
Description		neuromedin B	kinesin family member 23
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GO Annotations	Cellular Component	Extracellular Region Neuron Projection	Nucleus Nucleoplasm Centrosome Spindle Cytosol Kinesin Complex Microtubule Focal Adhesion Midbody Mitotic Spindle Flemming Body Centralspindlin Complex
	Molecular Function	Hormone Activity Neuropeptide Hormone Activity Protein Binding Neuromedin B Receptor Binding	Microtubule Motor Activity Protein Binding ATP Binding Microtubule Binding ATPase Activity
	Biological Process	Signal Transduction G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Cytosolic Calcium Ion Concentration Neuropeptide Signaling Pathway Cell-cell Signaling Positive Regulation Of Cell Population Proliferation Glucose Homeostasis Positive Regulation Of Hormone Secretion Negative Regulation Of Hormone Secretion Arachidonic Acid Secretion	Mitotic Spindle Elongation Mitotic Cytokinesis Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Microtubule-based Movement Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Positive Regulation Of Cytokinesis Mitotic Spindle Midzone Assembly
Pathways		Peptide ligand-binding receptors G alpha (q) signalling events	MHC class II antigen presentation COPI-dependent Golgi-to-ER retrograde traffic Mitotic Telophase/Cytokinesis Kinesins
Drugs
Diseases
GWAS		Autism spectrum disorder or schizophrenia ( 28540026) Bipolar disorder ( 31043756) Blood protein levels ( 30072576) Creatine kinase levels ( 29403010) P wave terminal force ( 28794112) Schizophrenia ( 29483656)	Mean reticulocyte volume ( 32888494) Rheumatoid arthritis (ACPA-positive) ( 24532676)
Interacting Genes		4 interacting genes: BIRC2 GADD45G NMBR TPP1	13 interacting genes: ACTA1 ARF3 CLK1 LATS2 PLK1 PPP1CB RACGAP1 RBM34 SUMO2 USP8 YWHAB YWHAG YWHAQ
Entrez ID		4828	9493
HPRD ID		01210	05455
Ensembl ID		ENSG00000197696	ENSG00000137807
Uniprot IDs		P08949	Q02241
PDB IDs		1C98 1C9A	3VHX
Enriched GO Terms of Interacting Partners?
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