NMB and FBXL22

Data Source:
BioGRID (affinity chromatography technology)

		NMB	FBXL22
Description		neuromedin B	F-box and leucine rich repeat protein 22
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Neuron Projection	Nucleus Nucleolus Cytosol SCF Ubiquitin Ligase Complex Z Disc
	Molecular Function	Hormone Activity Neuropeptide Hormone Activity Protein Binding Neuromedin B Receptor Binding	Protein Binding Ubiquitin Protein Ligase Activity
	Biological Process	Signal Transduction G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Cytosolic Calcium Ion Concentration Neuropeptide Signaling Pathway Cell-cell Signaling Positive Regulation Of Cell Population Proliferation Glucose Homeostasis Positive Regulation Of Hormone Secretion Negative Regulation Of Hormone Secretion Arachidonic Acid Secretion	G2/M Transition Of Mitotic Cell Cycle Protein Polyubiquitination SCF-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process Entrainment Of Circadian Clock By Photoperiod Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Post-translational Protein Modification Regulation Of Cell Cycle
Pathways		Peptide ligand-binding receptors G alpha (q) signalling events	Neddylation Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Autism spectrum disorder or schizophrenia ( 28540026) Bipolar disorder ( 31043756) Blood protein levels ( 30072576) Creatine kinase levels ( 29403010) P wave terminal force ( 28794112) Schizophrenia ( 29483656)	Chronic obstructive pulmonary disease or resting heart rate (pleiotropy) ( 30940143) Serum immune biomarker levels ( 32066700)
Interacting Genes		4 interacting genes: BIRC2 GADD45G NMBR TPP1	2 interacting genes: ACTN2 SKP1
Entrez ID		4828	283807
HPRD ID		01210	16432
Ensembl ID		ENSG00000197696	ENSG00000197361
Uniprot IDs		P08949	Q6P050
PDB IDs		1C98 1C9A
Enriched GO Terms of Interacting Partners?
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