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NKX2-2 and DLGAP4
Data Source:
BioGRID
(affinity chromatography technology)
NKX2-2
DLGAP4
Description
NK2 homeobox 2
DLG associated protein 4
Image
No pdb structure
No pdb structure
GO Annotations
Cellular Component
Chromatin
Nucleus
Nucleoplasm
Plasma Membrane
Neuromuscular Junction
Glutamatergic Synapse
Cholinergic Synapse
Postsynaptic Specialization
Molecular Function
RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding
DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
Cis-regulatory Region Sequence-specific DNA Binding
DNA-binding Transcription Activator Activity, RNA Polymerase II-specific
Transcription Factor Binding
Protein Binding
Molecular Adaptor Activity
Biological Process
Type B Pancreatic Cell Development
Pancreatic A Cell Fate Commitment
Type B Pancreatic Cell Fate Commitment
Pancreatic PP Cell Fate Commitment
Regulation Of Transcription By RNA Polymerase II
Smoothened Signaling Pathway
Brain Development
Response To Glucose
Oligodendrocyte Development
Spinal Cord Motor Neuron Differentiation
Spinal Cord Oligodendrocyte Cell Fate Specification
Optic Nerve Development
Cell Differentiation
Endocrine Pancreas Development
Response To Progesterone
Negative Regulation Of Neuron Differentiation
Positive Regulation Of Neuron Differentiation
Positive Regulation Of Transcription By RNA Polymerase II
Digestive Tract Development
Neuron Fate Specification
Astrocyte Differentiation
Positive Regulation Of Oligodendrocyte Differentiation
Ventral Spinal Cord Interneuron Fate Determination
Signaling
Regulation Of Postsynaptic Neurotransmitter Receptor Activity
Pathways
Regulation of gene expression in beta cells
Regulation of gene expression in endocrine-committed (NEUROG3+) progenitor cells
Neurexins and neuroligins
Neurexins and neuroligins
Drugs
Diseases
GWAS
Autism spectrum disorder (
30804558
)
Chronotype (
30696823
)
Ewing sarcoma (
30093639
)
Hyperglycemia in higher physical activity (
30327367
)
Lupus nephritis in systemic lupus erythematosus (
24925725
)
Refractive error (
32231278
)
Low density lipoprotein cholesterol levels (
32154731
)
Neuroblastoma or malignant cutaneous melanoma (
31605138
)
Interacting Genes
1 interacting genes:
OLIG2
32 interacting genes:
ABI2
ALDH16A1
ATPAF2
BIN1
DLG1
DLG3
DLG4
EXOC4
FHL3
FHL5
FKBP6
FYN
GRIN1
GRIN2D
MAGEA6
MPP7
MTUS2
NCK1
NCK2
PALS1
PLP2
PPP1R1B
SH3GL2
SH3RF1
SHANK2
SHANK3
SLC9A3R1
SLC9A3R2
SORBS2
SYNGAP1
UBASH3A
UBC
Entrez ID
4821
22839
HPRD ID
05213
16826
Ensembl ID
ENSG00000125820
ENSG00000080845
Uniprot IDs
O95096
A0A0B4J2C2
Q9Y2H0
PDB IDs
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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