ATP1B1 and CREG1

Data Source:
HPRD (in vitro, in vivo)

		ATP1B1	CREG1
Description		ATPase Na+/K+ transporting subunit beta 1	cellular repressor of E1A stimulated genes 1
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Sodium:potassium-exchanging ATPase Complex Caveola Intercalated Disc Membrane Basolateral Plasma Membrane Apical Plasma Membrane Lateral Plasma Membrane T-tubule Organelle Membrane Sperm Flagellum Sarcolemma Extracellular Exosome Extracellular Vesicle	Extracellular Region Extracellular Space Azurophil Granule Lumen Extracellular Exosome
	Molecular Function	ATPase Activator Activity Protein Binding Protein C-terminus Binding Protein Kinase Binding MHC Class II Protein Complex Binding Protein-macromolecule Adaptor Activity Protein Heterodimerization Activity ATPase Binding	Transcription Corepressor Activity
	Biological Process	Response To Hypoxia Cellular Calcium Ion Homeostasis Cellular Sodium Ion Homeostasis Cell Adhesion Establishment Or Maintenance Of Transmembrane Electrochemical Gradient Regulation Of Gene Expression Regulation Of Cardiac Muscle Contraction By Calcium Ion Signaling Cellular Potassium Ion Homeostasis Positive Regulation Of ATPase Activity Ion Transmembrane Transport Sodium Ion Transmembrane Transport Sodium Ion Export Across Plasma Membrane Protein Transport Into Plasma Membrane Raft ATP Metabolic Process Protein Stabilization Leukocyte Migration Relaxation Of Cardiac Muscle Cardiac Muscle Contraction Protein Localization To Plasma Membrane Membrane Repolarization Membrane Repolarization During Cardiac Muscle Cell Action Potential Cell Communication By Electrical Coupling Involved In Cardiac Conduction Cation Transmembrane Transport Positive Regulation Of Potassium Ion Transmembrane Transporter Activity Positive Regulation Of Sodium Ion Export Across Plasma Membrane Positive Regulation Of Calcium:sodium Antiporter Activity Positive Regulation Of Potassium Ion Import Across Plasma Membrane Positive Regulation Of Sodium:potassium-exchanging ATPase Activity Regulation Of Cardiac Conduction Potassium Ion Import Across Plasma Membrane	Regulation Of Transcription By RNA Polymerase II Multicellular Organism Development Regulation Of Growth Neutrophil Degranulation Negative Regulation Of Transcription, DNA-templated
Pathways		Basigin interactions Ion homeostasis Ion transport by P-type ATPases Potential therapeutics for SARS	Neutrophil degranulation
Drugs
Diseases
GWAS		Coronary artery disease ( 29212778 33020668) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Electrocardiographic traits ( 32602732 25055868) Fuchs's corneal dystrophy ( 28358029) Mitochondrial DNA levels ( 25240745) QT interval ( 23166209 29213071 24952745 19305409 29874175) Rosacea symptom severity ( 29771307)	Asthma ( 31959851) Blood protein levels ( 30072576 29875488)
Interacting Genes		21 interacting genes: AGTR1 BACE1 BARD1 BRCA1 CRIP2 DDAH2 EGFR EZH2 FXYD1 FXYD7 GCH1 HTR2B KMT2B LRIF1 NDRG2 PAXIP1 PSME1 TRIM14 TRMT2A TSC22D2 USP4	6 interacting genes: CAPN1 IGF2R RB1 RBL1 RBL2 TBP
Entrez ID		481	8804
HPRD ID		01663	09897
Ensembl ID		ENSG00000143153	ENSG00000143162
Uniprot IDs		A3KLL5 P05026	O75629
PDB IDs			1XHN
Enriched GO Terms of Interacting Partners?
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