NFIX and MLLT1

Data Source:
BioGRID (proximity labelling technology)

		NFIX	MLLT1
Description		nuclear factor I X	MLLT1 super elongation complex subunit
Image		No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus	Fibrillar Center Nucleoplasm Cytosol Transcription Elongation Factor Complex
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Protein Binding Sequence-specific Double-stranded DNA Binding	Protein Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II DNA Replication Regulation Of Transcription By RNA Polymerase II Transcription By RNA Polymerase II Positive Regulation Of Transcription By RNA Polymerase II	Regulation Of Transcription, DNA-templated Transcription By RNA Polymerase II Transcription Elongation From RNA Polymerase II Promoter Negative Regulation Of Protein Kinase Activity
Pathways		RNA Polymerase III Transcription Termination RNA Polymerase III Abortive And Retractive Initiation	Formation of RNA Pol II elongation complex RNA Polymerase II Pre-transcription Events RNA Polymerase II Transcription Elongation
Drugs
Diseases			Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia)
GWAS		Bipolar disorder ( 28115744) Body mass index ( 25673413) Brain morphology (MOSTest) ( 32665545) Clozapine-induced agranulocytosis ( 25187353) Granulocyte percentage of myeloid white cells ( 27863252) Heel bone mineral density ( 30598549) Hemoglobin ( 32888494) Intelligence (MTAG) ( 29326435) Lymphocyte counts ( 32888494) Mean corpuscular hemoglobin ( 32888494) Mean corpuscular volume ( 32888494) Mean reticulocyte volume ( 32888494) Monocyte count ( 32888494 27863252) Monocyte percentage of white cells ( 32888494 27863252) Plateletcrit ( 32888494) Refractive error ( 32231278)	Monocyte percentage of white cells ( 32888494) Oppositional defiant disorder dimensions in attention-deficit hyperactivity disorder ( 27021288)
Interacting Genes		8 interacting genes: JMJD6 MLH1 NFIB PIR QRICH1 RFX1 SKI ZNF614	12 interacting genes: AFF1 AFF4 ALKBH4 ARID1A BMI1 CBX8 H1-5 H3-4 MLLT10 PAF1 WDR5 YIF1A
Entrez ID		4784	4298
HPRD ID		01234	15933
Ensembl ID		ENSG00000008441	ENSG00000130382
Uniprot IDs		B4DHW2 Q14938	Q03111
PDB IDs			5J9S 6HPW 6HPX 6HPY 6HPZ 6HQ0 6HT0 6HT1 6T1I 6T1J 6T1L 6T1M 6T1N 6T1O
Enriched GO Terms of Interacting Partners?
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