NDUFV3 and MX2

Data Source:
BioGRID (affinity chromatography technology)

		NDUFV3	MX2
Description		NADH:ubiquinone oxidoreductase subunit V3	MX dynamin like GTPase 2
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GO Annotations	Cellular Component	Mitochondrion Mitochondrial Inner Membrane Mitochondrial Respiratory Chain Complex I	Nucleus Nuclear Pore Cytoplasm Cytosol Plasma Membrane Postsynaptic Density Microtubule Cytoskeleton Membrane Axon Cytoplasmic Vesicle Mitochondrial Membrane Dendritic Spine Head Presynapse Postsynaptic Endocytic Zone Membrane
	Molecular Function	RNA Binding Protein Binding NADH Dehydrogenase (ubiquinone) Activity	GTPase Activity Protein Binding GTP Binding Microtubule Binding
	Biological Process	Mitochondrial Electron Transport, NADH To Ubiquinone Mitochondrial Respiratory Chain Complex I Assembly Mitochondrial ATP Synthesis Coupled Electron Transport	Mitochondrial Fission Dynamin Family Protein Polymerization Involved In Mitochondrial Fission Defense Response Response To Virus Synaptic Vesicle Budding From Presynaptic Endocytic Zone Membrane Receptor Internalization Response To Interferon-alpha Regulation Of Nucleocytoplasmic Transport Regulation Of Synapse Structure Or Activity MRNA Transport Defense Response To Virus Regulation Of Cell Cycle Type I Interferon Signaling Pathway Membrane Fusion Postsynaptic Neurotransmitter Receptor Internalization
Pathways		Respiratory electron transport Complex I biogenesis	ISG15 antiviral mechanism Interferon alpha/beta signaling
Drugs		NADH Ubidecarenone
Diseases
GWAS			Cutaneous malignant melanoma ( 32341527) Melanoma ( 21983787 28212542) Nevus count or cutaneous melanoma ( 32341527 30429480) Parkinson disease and lewy body pathology ( 25663231)
Interacting Genes		1 interacting genes: PHYHIP	3 interacting genes: ATRIP EHMT2 PIAS2
Entrez ID		4731	4600
HPRD ID		03716	01001
Ensembl ID		ENSG00000160194	ENSG00000183486
Uniprot IDs		P56181	P20592
PDB IDs		5XTB 5XTD 5XTH 5XTI	4WHJ 4X0R 5UOT
Enriched GO Terms of Interacting Partners?
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