NDUFS8 and CDH16

Data Source:
BioGRID (two hybrid)

		NDUFS8	CDH16
Description		NADH:ubiquinone oxidoreductase core subunit S8	cadherin 16
Image			No pdb structure
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Respiratory Chain Complex I Mitochondrial Matrix	Integral Component Of Plasma Membrane Basolateral Plasma Membrane Extracellular Exosome
	Molecular Function	NADH Dehydrogenase Activity Protein Binding NADH Dehydrogenase (ubiquinone) Activity Metal Ion Binding 4 Iron, 4 Sulfur Cluster Binding	Calcium Ion Binding Protein Binding
	Biological Process	Mitochondrial Electron Transport, NADH To Ubiquinone Response To Oxidative Stress Aerobic Respiration Mitochondrial Respiratory Chain Complex I Assembly	Cell Adhesion Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Calcium-dependent Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules
Pathways		Respiratory electron transport Complex I biogenesis
Drugs		NADH
Diseases		Mitochondrial respiratory chain deficiencies (MRCD), including: Mitochondrial complex I deficiency (MT-C1D); Complex II deficiency (MT-C2D); Complex III deficiency (MT-C3D); Complex IV deficiency (MT-C4D); Complex V deficiency (MT-ATPSD); Leigh syndrome (LS); Kearns-Sayre Syndrome (KSS); LCHD deficiency (LCHD); Leber Hereditary Optic Neuropathy (LHON); Myoclonic Epilepsy and Ragged-Red Fiber Disease (MERRF); NARP; MELAS; ACAD9 deficiency; HADH deficiency; HIBCH deficiency; GRACILE syndrome
GWAS			HDL cholesterol levels in current drinkers ( 30698716) HDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716) HDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716)
Interacting Genes		2 interacting genes: GEM UBC	2 interacting genes: CTNNB1 G6PC1
Entrez ID		4728	1014
HPRD ID		03683	11929
Ensembl ID		ENSG00000110717	ENSG00000166589
Uniprot IDs		O00217	O75309
PDB IDs		5XTB 5XTD 5XTH 5XTI
Enriched GO Terms of Interacting Partners?
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