MYO9A and COL15A1

Data Source:
BioGRID (proximity labelling technology)

		MYO9A	COL15A1
Description		myosin IXA	collagen type XV alpha 1 chain
Image		No pdb structure
GO Annotations	Cellular Component	Cytosol Integral Component Of Membrane Unconventional Myosin Complex Axonal Growth Cone Synapse	Extracellular Region Collagen Type XV Trimer Extracellular Space Endoplasmic Reticulum Lumen Integral Component Of Membrane Extracellular Matrix Collagen-containing Extracellular Matrix Extracellular Exosome
	Molecular Function	Motor Activity Actin Binding GTPase Activator Activity Protein Binding ATP Binding Metal Ion Binding	Extracellular Matrix Structural Constituent Extracellular Matrix Structural Constituent Conferring Tensile Strength
	Biological Process	Visual Perception Cell Junction Assembly Intracellular Signal Transduction Positive Regulation Of GTPase Activity Establishment Of Epithelial Cell Apical/basal Polarity Regulation Of Small GTPase Mediated Signal Transduction Regulation Of Neuron Projection Arborization	Angiogenesis Endothelial Cell Morphogenesis Cell Adhesion Signal Transduction Extracellular Matrix Organization Collagen Catabolic Process
Pathways		Rho GTPase cycle	Collagen degradation Collagen biosynthesis and modifying enzymes Assembly of collagen fibrils and other multimeric structures Collagen chain trimerization
Drugs
Diseases
GWAS		Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223) Height ( 20881960) Macular thickness ( 30535121) Metabolite levels (HVA/MHPG ratio) ( 23319000) Rate of cognitive decline in mild cognitive impairment (time interaction) ( 22833209) Red blood cell count ( 27863252) Serum uric acid levels ( 30993211) Triglyceride levels ( 32203549 30108155) Urate levels ( 31578528)	Advanced age-related macular degeneration ( 26691988) Asthma ( 31959851 32296059) Blood protein levels ( 30072576 29875488) Brain morphology (MOSTest) ( 32665545) Chronic obstructive pulmonary disease ( 30804561) Epithelial ovarian cancer ( 25134534) Fractures (paediatric) ( 32742401) Gut microbiota alpha diversity (Shannon index) ( 33208821) Gut microbiota relative abundance (unclassified genus belonging to the order Clostridiales) ( 33208821) Height ( 28552196) Lateral ventricle temporal horn volume ( 31530798) Pulse pressure ( 30224653 30578418)
Interacting Genes		5 interacting genes: CDC42 ERBB2 MTNR1A POLR2M RHOA
Entrez ID		4649	1306
HPRD ID		05341	00380
Ensembl ID		ENSG00000066933	ENSG00000204291
Uniprot IDs		B2RTY4	B3KTP7 P39059
PDB IDs			3N3F
Enriched GO Terms of Interacting Partners?
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