MX2 and NDUFV3

Data Source:
BioGRID (affinity chromatography technology)

		MX2	NDUFV3
Description		MX dynamin like GTPase 2	NADH:ubiquinone oxidoreductase subunit V3
Image
GO Annotations	Cellular Component	Nucleus Nuclear Pore Cytoplasm Cytosol Plasma Membrane Postsynaptic Density Microtubule Cytoskeleton Membrane Axon Cytoplasmic Vesicle Mitochondrial Membrane Dendritic Spine Head Presynapse Postsynaptic Endocytic Zone Membrane	Mitochondrion Mitochondrial Inner Membrane Mitochondrial Respiratory Chain Complex I
	Molecular Function	GTPase Activity Protein Binding GTP Binding Microtubule Binding	RNA Binding Protein Binding NADH Dehydrogenase (ubiquinone) Activity
	Biological Process	Mitochondrial Fission Dynamin Family Protein Polymerization Involved In Mitochondrial Fission Defense Response Response To Virus Synaptic Vesicle Budding From Presynaptic Endocytic Zone Membrane Receptor Internalization Response To Interferon-alpha Regulation Of Nucleocytoplasmic Transport Regulation Of Synapse Structure Or Activity MRNA Transport Defense Response To Virus Regulation Of Cell Cycle Type I Interferon Signaling Pathway Membrane Fusion Postsynaptic Neurotransmitter Receptor Internalization	Mitochondrial Electron Transport, NADH To Ubiquinone Mitochondrial Respiratory Chain Complex I Assembly Mitochondrial ATP Synthesis Coupled Electron Transport
Pathways		ISG15 antiviral mechanism Interferon alpha/beta signaling	Respiratory electron transport Complex I biogenesis
Drugs			NADH Ubidecarenone
Diseases
GWAS		Cutaneous malignant melanoma ( 32341527) Melanoma ( 21983787 28212542) Nevus count or cutaneous melanoma ( 32341527 30429480) Parkinson disease and lewy body pathology ( 25663231)
Interacting Genes		3 interacting genes: ATRIP EHMT2 PIAS2	1 interacting genes: PHYHIP
Entrez ID		4600	4731
HPRD ID		01001	03716
Ensembl ID		ENSG00000183486	ENSG00000160194
Uniprot IDs		P20592	P56181
PDB IDs		4WHJ 4X0R 5UOT	5XTB 5XTD 5XTH 5XTI
Enriched GO Terms of Interacting Partners?
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