MVK and GLTP

Data Source:
BioGRID (proximity labelling technology)

		MVK	GLTP
Description		mevalonate kinase	glycolipid transfer protein
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GO Annotations	Cellular Component	Peroxisome Cytosol Intracellular Membrane-bounded Organelle	Cytosol Membrane
	Molecular Function	Magnesium Ion Binding Mevalonate Kinase Activity Protein Binding ATP Binding Identical Protein Binding	Protein Binding Lipid Binding Glycolipid Transfer Activity Identical Protein Binding Glycolipid Binding Lipid Transfer Activity Ceramide 1-phosphate Binding Ceramide 1-phosphate Transfer Activity
	Biological Process	Cholesterol Biosynthetic Process Isoprenoid Biosynthetic Process Phosphorylation Isopentenyl Diphosphate Biosynthetic Process, Mevalonate Pathway Regulation Of Cholesterol Biosynthetic Process Negative Regulation Of Inflammatory Response	Glycosphingolipid Metabolic Process Ceramide Transport Glycolipid Transport Intermembrane Lipid Transfer Ceramide 1-phosphate Transport
Pathways		Cholesterol biosynthesis Activation of gene expression by SREBF (SREBP)	Glycosphingolipid metabolism
Drugs		Farnesyl thiopyrophosphate	Lauric acid Sphingosine Capric acid Lactose
Diseases		Mevalonate kinase deficiency; Hyperimmunoglobulinemia D; Mevalonic aciduria
GWAS		Aspartate aminotransferase levels ( 29403010) Fish- and plant-related diet ( 32066663) HDL cholesterol ( 24097068 18193043 20864672 19060906 30275531 25961943 20686565) HDL cholesterol levels ( 28334899) High density lipoprotein cholesterol levels ( 29403010) Low density lipoprotein cholesterol levels ( 32154731) Mean platelet volume ( 32888494) Neutrophil count ( 29403010) Non-oily fish consumption ( 32066663) Oily fish consumption ( 32066663) Pork consumption ( 32066663) Red cell distribution width ( 28957414)	Bipolar disorder ( 31043756) Hemoglobin ( 32888494) Metabolic syndrome ( 20694148)
Interacting Genes		4 interacting genes: EWSR1 POT1 RNF141 TERF1	1 interacting genes: CMTM5
Entrez ID		4598	51228
HPRD ID		02015	16409
Ensembl ID		ENSG00000110921	ENSG00000139433
Uniprot IDs		B2RDU6 B7Z301 F5H8H2 Q03426	A0A024RBI7 Q9NZD2
PDB IDs		2R3V	1SWX 1SX6 2EUK 2EUM 2EVD 2EVL 2EVS 2EVT 3RIC 3RWV 3RZN 3S0I 3S0K 4GH0 4GHP 4GHS 4GIX 4GJQ 4GVT 4GXD 4GXG 4H2Z
Enriched GO Terms of Interacting Partners?
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