MOV10 and ATP5PB

Data Source:
BioGRID (affinity chromatography technology)

		MOV10	ATP5PB
Description		Mov10 RISC complex RNA helicase	ATP synthase peripheral stalk-membrane subunit b
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	P-body Extracellular Space Nucleus Cytosol Cytoplasmic Stress Granule Cytoplasmic Ribonucleoprotein Granule P Granule	Mitochondrial Proton-transporting ATP Synthase Complex, Coupling Factor F(o) Nucleus Nucleoplasm Mitochondrion Mitochondrial Inner Membrane Mitochondrial Proton-transporting ATP Synthase Complex Mitochondrial Matrix Membrane
	Molecular Function	RNA Binding Protein Binding ATP Binding 5'-3' RNA Helicase Activity	Protein Binding Proton-transporting ATP Synthase Activity, Rotational Mechanism
	Biological Process	Wnt Signaling Pathway, Calcium Modulating Pathway Negative Regulation Of Transposition, RNA-mediated Positive Regulation Of Gene Expression Negative Regulation Of Gene Expression Viral Process Post-transcriptional Gene Silencing By RNA Gene Silencing By MiRNA MRNA Cleavage Involved In Gene Silencing By MiRNA Regulation Of Megakaryocyte Differentiation Defense Response To Virus Positive Regulation Of MRNA Catabolic Process 3'-UTR-mediated MRNA Destabilization Regulation Of Neuron Projection Arborization	ATP Biosynthetic Process ATP Synthesis Coupled Proton Transport Substantia Nigra Development Cristae Formation Mitochondrial ATP Synthesis Coupled Proton Transport
Pathways		Pre-NOTCH Transcription and Translation Oxidative Stress Induced Senescence Oncogene Induced Senescence Ca2+ pathway TP53 Regulates Metabolic Genes MAPK6/MAPK4 signaling Transcriptional Regulation by VENTX Regulation of RUNX1 Expression and Activity RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function Regulation of PTEN mRNA translation Competing endogenous RNAs (ceRNAs) regulate PTEN translation Transcriptional Regulation by MECP2 Transcriptional Regulation by MECP2 Estrogen-dependent gene expression Regulation of MECP2 expression and activity NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux	Formation of ATP by chemiosmotic coupling Cristae formation
Drugs
Diseases
GWAS		Blood pressure ( 21909110) Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Body size at age 10 ( 32376654) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (min-P) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical surface area (visual PC2) ( 32198502) Cortical thickness (min-P) ( 32665545) Cortical thickness (MOSTest) ( 32665545) Diastolic blood pressure ( 27841878 21909115 28739976 27618452 25249183 30487518) Diastolic blood pressure x alcohol consumption interaction (2df test) ( 29912962) Height ( 31562340) Hip circumference adjusted for BMI ( 25673412) Hypertension ( 21909115 25249183 30487518) Mean arterial pressure ( 30487518) Mean arterial pressure x alcohol consumption interaction (2df test) ( 29912962) Medication use (diuretics) ( 31015401) Platelet count ( 32888494) Plateletcrit ( 32888494) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545) Systolic blood pressure ( 27841878 21909115 28739976 27618452 25249183 30487518) Systolic blood pressure x alcohol consumption interaction (2df test) ( 29912962)
Interacting Genes		1 interacting genes: EIF2AK2	3 interacting genes: CLIC1 SPP1 TRIM14
Entrez ID		4343	515
HPRD ID		14732	04467
Ensembl ID		ENSG00000155363	ENSG00000116459
Uniprot IDs		Q5JR04 Q9HCE1	P24539 Q08ET0
PDB IDs
Enriched GO Terms of Interacting Partners?
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