MOV10 and ADORA3

Data Source:
HPRD (in vitro)

		MOV10	ADORA3
Description		Mov10 RISC complex RNA helicase	adenosine A3 receptor
Image		No pdb structure
GO Annotations	Cellular Component	P-body Extracellular Space Nucleus Cytosol Cytoplasmic Stress Granule Cytoplasmic Ribonucleoprotein Granule P Granule	Plasma Membrane Integral Component Of Plasma Membrane
	Molecular Function	RNA Binding Protein Binding ATP Binding 5'-3' RNA Helicase Activity	G Protein-coupled Adenosine Receptor Activity
	Biological Process	Wnt Signaling Pathway, Calcium Modulating Pathway Negative Regulation Of Transposition, RNA-mediated Positive Regulation Of Gene Expression Negative Regulation Of Gene Expression Viral Process Post-transcriptional Gene Silencing By RNA Gene Silencing By MiRNA MRNA Cleavage Involved In Gene Silencing By MiRNA Regulation Of Megakaryocyte Differentiation Defense Response To Virus Positive Regulation Of MRNA Catabolic Process 3'-UTR-mediated MRNA Destabilization Regulation Of Neuron Projection Arborization	G Protein-coupled Adenosine Receptor Signaling Pathway Inflammatory Response Signal Transduction G Protein-coupled Receptor Signaling Pathway Activation Of Adenylate Cyclase Activity Regulation Of Heart Contraction Negative Regulation Of Cell Population Proliferation Response To Wounding Negative Regulation Of Cell Migration Negative Regulation Of NF-kappaB Transcription Factor Activity
Pathways		Pre-NOTCH Transcription and Translation Oxidative Stress Induced Senescence Oncogene Induced Senescence Ca2+ pathway TP53 Regulates Metabolic Genes MAPK6/MAPK4 signaling Transcriptional Regulation by VENTX Regulation of RUNX1 Expression and Activity RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function Regulation of PTEN mRNA translation Competing endogenous RNAs (ceRNAs) regulate PTEN translation Transcriptional Regulation by MECP2 Transcriptional Regulation by MECP2 Estrogen-dependent gene expression Regulation of MECP2 expression and activity NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux	Adenosine P1 receptors G alpha (i) signalling events
Drugs			Caffeine Adenosine Enprofylline Aminophylline Piclidenoson Fostamatinib
Diseases
GWAS		Blood pressure ( 21909110) Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Body size at age 10 ( 32376654) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (min-P) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical surface area (visual PC2) ( 32198502) Cortical thickness (min-P) ( 32665545) Cortical thickness (MOSTest) ( 32665545) Diastolic blood pressure ( 27841878 21909115 28739976 27618452 25249183 30487518) Diastolic blood pressure x alcohol consumption interaction (2df test) ( 29912962) Height ( 31562340) Hip circumference adjusted for BMI ( 25673412) Hypertension ( 21909115 25249183 30487518) Mean arterial pressure ( 30487518) Mean arterial pressure x alcohol consumption interaction (2df test) ( 29912962) Medication use (diuretics) ( 31015401) Platelet count ( 32888494) Plateletcrit ( 32888494) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545) Systolic blood pressure ( 27841878 21909115 28739976 27618452 25249183 30487518) Systolic blood pressure x alcohol consumption interaction (2df test) ( 29912962)	Energy intake ( 30071075) Obesity-related traits ( 23251661)
Interacting Genes		1 interacting genes: EIF2AK2
Entrez ID		4343	140
HPRD ID		14732	08984
Ensembl ID		ENSG00000155363	ENSG00000282608
Uniprot IDs		Q5JR04 Q9HCE1	A0A0J9YWR0 H6VQ59 P0DMS8
PDB IDs			1OEA 1R7N
Enriched GO Terms of Interacting Partners?
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