MGAT2 and TIMM9

Data Source:
BioGRID (proximity labelling technology)

		MGAT2	TIMM9
Description		alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase	translocase of inner mitochondrial membrane 9
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GO Annotations	Cellular Component	Golgi Membrane Golgi Apparatus Golgi Stack Membrane Integral Component Of Membrane	Mitochondrion Mitochondrial Inner Membrane Mitochondrial Intermembrane Space Mitochondrial Intermembrane Space Protein Transporter Complex
	Molecular Function	Alpha-1,6-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase Activity Manganese Ion Binding Carbohydrate Binding Protein Homodimerization Activity	Protein Binding Zinc Ion Binding Protein Homodimerization Activity Chaperone Binding Protein Transporter Activity
	Biological Process	Protein N-linked Glycosylation Oligosaccharide Biosynthetic Process Protein Phosphopantetheinylation Protein N-linked Glycosylation Via Asparagine	Protein Targeting To Mitochondrion Sensory Perception Of Sound Protein Insertion Into Mitochondrial Inner Membrane Chaperone-mediated Protein Transport
Pathways		Defective MGAT2 causes MGAT2-CDG (CDG-2a) Maturation of spike protein Reactions specific to the complex N-glycan synthesis pathway	Mitochondrial protein import Mitochondrial protein import
Drugs
Diseases		Congenital disorders of glycosylation (CDG) type II
GWAS		Blood protein levels ( 30072576 29875488)	Brain morphology (MOSTest) ( 32665545)
Interacting Genes
Entrez ID		4247	26520
HPRD ID		04013	09574
Ensembl ID		ENSG00000168282	ENSG00000100575
Uniprot IDs		Q10469	A0A024R648 A0A1W2PQS5 A0A1W2PRH9 G3V502 Q9Y5J7
PDB IDs		5VCM 5VCR 5VCS	2BSK 7CGP
Enriched GO Terms of Interacting Partners?
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