MFGE8 and TM6SF1

Data Source:
BioGRID (affinity chromatography technology)

		MFGE8	TM6SF1
Description		milk fat globule EGF and factor V/VIII domain containing	transmembrane 6 superfamily member 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Endoplasmic Reticulum Lumen External Side Of Plasma Membrane Membrane Extrinsic Component Of Plasma Membrane Collagen-containing Extracellular Matrix Extracellular Exosome Extracellular Vesicle	Lysosomal Membrane Integral Component Of Membrane
	Molecular Function	Phosphatidylserine Binding Integrin Binding Extracellular Matrix Structural Constituent Phosphatidylethanolamine Binding	Molecular_function
	Biological Process	Angiogenesis Phagocytosis, Recognition Phagocytosis, Engulfment Cell Adhesion Single Fertilization Apoptotic Cell Clearance Post-translational Protein Modification Cellular Protein Metabolic Process Positive Regulation Of Phagocytosis	Biological_process
Pathways		Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) Post-translational protein phosphorylation Amyloid fiber formation
Drugs
Diseases
GWAS		Blood protein levels ( 30072576 29875488 28240269) Coronary artery disease ( 32469254 26343387 33020668) Coronary artery disease (myocardial infarction, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease) ( 28714975) Height ( 31562340) Pulse pressure ( 27841878) Squamous cell lung carcinoma ( 28604730)	Diastolic blood pressure ( 27841878) Lymphocyte counts ( 32888494) Monocyte count ( 32888494)
Interacting Genes			2 interacting genes: MFF PEX5
Entrez ID		4240	53346
HPRD ID		03789	08411
Ensembl ID		ENSG00000140545	ENSG00000136404
Uniprot IDs		B3KTQ2 B4E396 Q08431	Q6P4D7 Q9BZW5
PDB IDs
Enriched GO Terms of Interacting Partners?
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