LSAMP and ATP6V1A

Data Source:
BioGRID (proximity labelling technology)

		LSAMP	ATP6V1A
Description		limbic system associated membrane protein	ATPase H+ transporting V1 subunit A
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Region Cytosol Plasma Membrane Anchored Component Of Membrane	Nucleoplasm Lysosomal Membrane Cytosol Plasma Membrane Microvillus Apical Plasma Membrane Proton-transporting Two-sector ATPase Complex Proton-transporting V-type ATPase, V1 Domain Intracellular Membrane-bounded Organelle Extracellular Exosome
	Molecular Function	Protein Binding	ATP Binding ATPase Activity Proton-transporting ATP Synthase Activity, Rotational Mechanism Proton-transporting ATPase Activity, Rotational Mechanism
	Biological Process	Cell Adhesion Nervous System Development	Cellular Iron Ion Homeostasis Insulin Receptor Signaling Pathway ATP Synthesis Coupled Proton Transport Regulation Of Macroautophagy Transferrin Transport Ion Transmembrane Transport Cellular Response To Increased Oxygen Levels Phagosome Acidification Proton Transmembrane Transport
Pathways		Post-translational modification: synthesis of GPI-anchored proteins	ROS and RNS production in phagocytes Insulin receptor recycling Transferrin endocytosis and recycling Amino acids regulate mTORC1 Ion channel transport
Drugs			Alendronic acid Etidronic acid Tiludronic acid Bafilomycin A1 Bafilomycin B1
Diseases
GWAS		Blood protein levels ( 30072576 29875488) Chronotype ( 30696823) Colorectal or endometrial cancer ( 26621817) Emphysema imaging phenotypes ( 26030696) Experiencing mood swings ( 29500382) Feeling miserable ( 29500382) Fish- and plant-related diet ( 32066663) General factor of neuroticism ( 30867560) Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223) Hip circumference ( 28552196) Itch intensity from mosquito bite adjusted by bite size ( 28199695) Systemising ( 31508503) Tourette's syndrome or obsessive-compulsive disorder ( 25158072)	Prostate cancer ( 23535732)
Interacting Genes		3 interacting genes: NEGR1 NTM PRNP	6 interacting genes: ANXA7 CDC42 CDKN1A SMN1 TK1 TUFM
Entrez ID		4045	523
HPRD ID		09128	06120
Ensembl ID		ENSG00000185565	ENSG00000114573
Uniprot IDs		B7Z661 Q13449	P38606
PDB IDs
Enriched GO Terms of Interacting Partners?
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