LOX and ZNF202

Data Source:
BioGRID (affinity chromatography technology)

		LOX	ZNF202
Description		lysyl oxidase	zinc finger protein 202
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Region Collagen Trimer Extracellular Space Nucleus Extracellular Matrix	Chromosome Nucleolus Nuclear Body
	Molecular Function	Protein-lysine 6-oxidase Activity Copper Ion Binding Protein Binding Collagen Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific Protein Binding Metal Ion Binding
	Biological Process	Osteoblast Differentiation Regulation Of Protein Phosphorylation Cellular Protein Modification Process Heart Development Regulation Of Gene Expression Regulation Of Striated Muscle Tissue Development Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Peptidyl-lysine Oxidation Protein Phosphopantetheinylation Extracellular Matrix Organization Collagen Fibril Organization Bone Mineralization Lung Development Platelet-derived Growth Factor Receptor-beta Signaling Pathway Ascending Aorta Development Descending Aorta Development Wound Healing Response To Drug Regulation Of Apoptotic Process Protein Kinase B Signaling Regulation Of Megakaryocyte Differentiation Muscle Cell Cellular Homeostasis Elastic Fiber Assembly Blood Vessel Morphogenesis Response To Steroid Hormone Muscle Fiber Development Cell Chemotaxis Connective Tissue Development DNA Biosynthetic Process Regulation Of Receptor Binding Regulation Of Bone Development Cellular Response To Chemokine Regulation Of Platelet-derived Growth Factor Receptor-beta Signaling Pathway	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II Lipid Metabolic Process
Pathways		Elastic fibre formation Crosslinking of collagen fibrils	Generic Transcription Pathway
Drugs
Diseases
GWAS		Central corneal thickness ( 32528159) Coronary artery disease ( 28714974) Intraocular pressure ( 29617998) Lung function (FEV1/FVC) ( 30804560) Thiazide-induced adverse metabolic effects in hypertensive patients ( 23400010) Youthful appearance (self-reported) ( 32339537)	Response to antipsychotic therapy (extrapyramidal side effects) ( 19875103) Response to citalopram or escitalopram in depression ( 27622933)
Interacting Genes		8 interacting genes: DHDDS DPT ELN H1-1 H1-5 H2BC11 H2BC21 RAF1	24 interacting genes: CARD10 CEP70 EAF1 KRT40 KRTAP10-3 LMO4 MAD2L1BP MCC MEOX2 MTIF3 MZF1 NAA10 NAA11 PCBD1 SCAND1 SCNM1 SEPHS1 SNX2 SSX2IP ZNF250 ZNF438 ZNF473 ZNF835 ZNF837
Entrez ID		4015	7753
HPRD ID		01087	04577
Ensembl ID		ENSG00000113083	ENSG00000166261
Uniprot IDs		B0AZT2 B7ZAJ4 D0PNI2 P28300	A0A024R3M3 B3KN61 O95125
PDB IDs
Enriched GO Terms of Interacting Partners?
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