LOX and SNX24

Data Source:
BioGRID (proximity labelling technology)

		LOX	SNX24
Description		lysyl oxidase	sorting nexin 24
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Region Collagen Trimer Extracellular Space Nucleus Extracellular Matrix	Cytoplasmic Vesicle Membrane
	Molecular Function	Protein-lysine 6-oxidase Activity Copper Ion Binding Protein Binding Collagen Binding	Protein Binding Phosphatidylinositol Phosphate Binding
	Biological Process	Osteoblast Differentiation Regulation Of Protein Phosphorylation Cellular Protein Modification Process Heart Development Regulation Of Gene Expression Regulation Of Striated Muscle Tissue Development Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Peptidyl-lysine Oxidation Protein Phosphopantetheinylation Extracellular Matrix Organization Collagen Fibril Organization Bone Mineralization Lung Development Platelet-derived Growth Factor Receptor-beta Signaling Pathway Ascending Aorta Development Descending Aorta Development Wound Healing Response To Drug Regulation Of Apoptotic Process Protein Kinase B Signaling Regulation Of Megakaryocyte Differentiation Muscle Cell Cellular Homeostasis Elastic Fiber Assembly Blood Vessel Morphogenesis Response To Steroid Hormone Muscle Fiber Development Cell Chemotaxis Connective Tissue Development DNA Biosynthetic Process Regulation Of Receptor Binding Regulation Of Bone Development Cellular Response To Chemokine Regulation Of Platelet-derived Growth Factor Receptor-beta Signaling Pathway	Protein Transport
Pathways		Elastic fibre formation Crosslinking of collagen fibrils
Drugs
Diseases
GWAS		Central corneal thickness ( 32528159) Coronary artery disease ( 28714974) Intraocular pressure ( 29617998) Lung function (FEV1/FVC) ( 30804560) Thiazide-induced adverse metabolic effects in hypertensive patients ( 23400010) Youthful appearance (self-reported) ( 32339537)	Brain morphology (MOSTest) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Glucose homeostasis traits ( 25524916) HDL cholesterol levels ( 32203549) Mean platelet volume ( 32888494) Plateletcrit ( 27863252) Subcortical volume (MOSTest) ( 32665545)
Interacting Genes		8 interacting genes: DHDDS DPT ELN H1-1 H1-5 H2BC11 H2BC21 RAF1	3 interacting genes: POU2F1 SH3GL3 YWHAZ
Entrez ID		4015	28966
HPRD ID		01087	15413
Ensembl ID		ENSG00000113083	ENSG00000064652
Uniprot IDs		B0AZT2 B7ZAJ4 D0PNI2 P28300	Q9Y343
PDB IDs			4AZ9
Enriched GO Terms of Interacting Partners?
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