LOX and GAP43

Data Source:
BioGRID (two hybrid)

		LOX	GAP43
Description		lysyl oxidase	growth associated protein 43
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Region Collagen Trimer Extracellular Space Nucleus Extracellular Matrix	Cytoplasm Plasma Membrane Postsynaptic Density Dendrite Filopodium Membrane Growth Cone Membrane Perikaryon GABA-ergic Synapse
	Molecular Function	Protein-lysine 6-oxidase Activity Copper Ion Binding Protein Binding Collagen Binding	Phosphatidylserine Binding Protein Binding Calmodulin Binding Lysophosphatidic Acid Binding Phosphatidylinositol Phosphate Binding
	Biological Process	Osteoblast Differentiation Regulation Of Protein Phosphorylation Cellular Protein Modification Process Heart Development Regulation Of Gene Expression Regulation Of Striated Muscle Tissue Development Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Peptidyl-lysine Oxidation Protein Phosphopantetheinylation Extracellular Matrix Organization Collagen Fibril Organization Bone Mineralization Lung Development Platelet-derived Growth Factor Receptor-beta Signaling Pathway Ascending Aorta Development Descending Aorta Development Wound Healing Response To Drug Regulation Of Apoptotic Process Protein Kinase B Signaling Regulation Of Megakaryocyte Differentiation Muscle Cell Cellular Homeostasis Elastic Fiber Assembly Blood Vessel Morphogenesis Response To Steroid Hormone Muscle Fiber Development Cell Chemotaxis Connective Tissue Development DNA Biosynthetic Process Regulation Of Receptor Binding Regulation Of Bone Development Cellular Response To Chemokine Regulation Of Platelet-derived Growth Factor Receptor-beta Signaling Pathway	Protein Kinase C-activating G Protein-coupled Receptor Signaling Pathway Response To Wounding Glial Cell Differentiation Axon Choice Point Recognition Axon Regeneration Regulation Of Growth Tissue Regeneration Cell Fate Commitment Regulation Of Filopodium Assembly Regulation Of Postsynaptic Specialization Assembly
Pathways		Elastic fibre formation Crosslinking of collagen fibrils	L1CAM interactions
Drugs
Diseases
GWAS		Central corneal thickness ( 32528159) Coronary artery disease ( 28714974) Intraocular pressure ( 29617998) Lung function (FEV1/FVC) ( 30804560) Thiazide-induced adverse metabolic effects in hypertensive patients ( 23400010) Youthful appearance (self-reported) ( 32339537)	Borderline personality disorder ( 28632202) Breast size ( 22747683) Metabolite levels ( 23823483) Proliferative diabetic retinopathy ( 31482010) Response to cognitive-behavioural therapy in anxiety disorder ( 26989097) Seasonality and depression ( 30217971) Urate levels in obese individuals ( 25811787)
Interacting Genes		8 interacting genes: DHDDS DPT ELN H1-1 H1-5 H2BC11 H2BC21 RAF1	8 interacting genes: CALM1 CSNK2A1 ELAVL4 PLCD1 PRKCB PRKCD RABEP1 SPTAN1
Entrez ID		4015	2596
HPRD ID		01087	01198
Ensembl ID		ENSG00000113083	ENSG00000172020
Uniprot IDs		B0AZT2 B7ZAJ4 D0PNI2 P28300	P17677 Q5U058
PDB IDs
Enriched GO Terms of Interacting Partners?
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