Wiki-MPM
About
Search
Browse
People
Funding
Updates
Search
LAG3 and GNAI2
Data Source:
BioGRID
(affinity chromatography technology)
LAG3
GNAI2
Description
lymphocyte activating 3
G protein subunit alpha i2
Image
No pdb structure
GO Annotations
Cellular Component
Extracellular Region
Plasma Membrane
External Side Of Plasma Membrane
Integral Component Of Membrane
Nucleoplasm
Cytoplasm
Centrosome
Cytosol
Heterotrimeric G-protein Complex
Plasma Membrane
Membrane
Dendrite
Midbody
Cell Body
Membrane Raft
Synapse
Extracellular Exosome
Extracellular Vesicle
Molecular Function
Antigen Binding
Transmembrane Signaling Receptor Activity
Protein Binding
MHC Class II Protein Binding
G Protein-coupled Receptor Binding
GTPase Activity
Protein Binding
GTP Binding
G-protein Beta/gamma-subunit Complex Binding
Metal Ion Binding
Biological Process
Adaptive Immune Response
Plasmacytoid Dendritic Cell Activation
Cell Surface Receptor Signaling Pathway
Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II
Negative Regulation Of Interleukin-2 Production
Negative Regulation Of Regulatory T Cell Differentiation
Positive Regulation Of Natural Killer Cell Mediated Cytotoxicity
Regulation Of Immune Response
G Protein-coupled Adenosine Receptor Signaling Pathway
Protein Folding
Cell Cycle
Signal Transduction
G Protein-coupled Receptor Signaling Pathway
Adenylate Cyclase-modulating G Protein-coupled Receptor Signaling Pathway
Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway
Adenylate Cyclase-inhibiting G Protein-coupled Receptor Signaling Pathway
Negative Regulation Of Adenylate Cyclase Activity
G Protein-coupled Acetylcholine Receptor Signaling Pathway
Gamma-aminobutyric Acid Signaling Pathway
Response To Nutrient
Cell Population Proliferation
Positive Regulation Of Cell Population Proliferation
Positive Regulation Of Cell Migration
Positive Regulation Of Superoxide Anion Generation
Positive Regulation Of NAD(P)H Oxidase Activity
Positive Regulation Of Urine Volume
Positive Regulation Of Renal Sodium Excretion
Negative Regulation Of Calcium Ion-dependent Exocytosis
Positive Regulation Of Insulin Receptor Signaling Pathway
Negative Regulation Of Synaptic Transmission
Cell Division
Regulation Of Calcium Ion Transport
Positive Regulation Of ERK1 And ERK2 Cascade
Negative Regulation Of Adenylate Cyclase-activating Adrenergic Receptor Signaling Pathway Involved In Heart Process
Negative Regulation Of Protein Tyrosine Phosphatase Activity
Positive Regulation Of Vascular Associated Smooth Muscle Cell Proliferation
Positive Regulation Of Neural Precursor Cell Proliferation
Negative Regulation Of Apoptotic Signaling Pathway
Pathways
MHC class II antigen presentation
PLC beta mediated events
PLC beta mediated events
Adenylate cyclase inhibitory pathway
Adenylate cyclase inhibitory pathway
G-protein activation
ADP signalling through P2Y purinoceptor 12
Adrenaline,noradrenaline inhibits insulin secretion
Adrenaline,noradrenaline inhibits insulin secretion
G alpha (s) signalling events
G alpha (i) signalling events
G alpha (i) signalling events
G alpha (z) signalling events
Regulation of insulin secretion
Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding
Extra-nuclear estrogen signaling
ADORA2B mediated anti-inflammatory cytokines production
Drugs
Diseases
Adrenal carcinoma
GWAS
Blood protein levels (
30072576
)
Body mass index (
26426971
)
Body size at age 10 (
32376654
)
Brain morphology (min-P) (
32665545
)
Brain morphology (MOSTest) (
32665545
)
Cortical surface area (MOSTest) (
32665545
)
Lymphocyte counts (
32888494
)
Lymphocyte percentage of white cells (
32888494
)
Monocyte count (
32888494
)
Morning person (
30696823
)
Sleep duration (short sleep) (
30846698
)
Subcortical volume (min-P) (
32665545
)
Subcortical volume (MOSTest) (
32665545
)
Interacting Genes
2 interacting genes:
CEBPZ
CENPJ
64 interacting genes:
ADCY1
ADORA1
ADRA2A
ADRA2B
ADRB2
AGTR2
C5AR1
CAV1
CCR5
CHRM1
CNR1
CXCL8
CXCR1
CXCR2
DRD2
EDNRA
EGFR
EYA1
EYA2
F2R
FPR1
GNB2
GNB4
GPSM2
GPSM3
IGF1R
ITCH
KRT31
KRT40
KRTAP10-8
LHB
LHCGR
LPAR3
LTB4R
MDFI
MRGPRX1
MTNR1A
MTNR1B
NGB
NOTCH2NLA
NPM1
NUCB1
OPRD1
OPRM1
P2RY12
PCP2
PLSCR1
PTEN
PTPRU
RASD1
RGS12
RGS14
RGS16
RGS18
RGS19
RGS20
RGS4
RGS5
RIC8A
TBXA2R
TRIP6
TSHR
TTC1
TUBA4A
Entrez ID
3902
2771
HPRD ID
01077
00764
Ensembl ID
ENSG00000089692
ENSG00000114353
Uniprot IDs
P18627
B3KP24
B3KX51
P04899
PDB IDs
6D9H
Enriched GO Terms of Interacting Partners
?
Tagcloud
?
Tagcloud (Difference)
?
Tagcloud (Intersection)
?