KIR3DL1 and FPR1

Data Source:
BioGRID (affinity chromatography technology)

		KIR3DL1	FPR1
Description		killer cell immunoglobulin like receptor, three Ig domains and long cytoplasmic tail 1	formyl peptide receptor 1
Image			No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane	Cytoplasm Plasma Membrane Integral Component Of Membrane Secretory Granule Membrane Azurophil Granule Membrane Ficolin-1-rich Granule Membrane
	Molecular Function	Amyloid-beta Binding Protein Binding HLA-B Specific Inhibitory MHC Class I Receptor Activity	G Protein-coupled Receptor Binding Complement Receptor Activity G Protein-coupled Receptor Activity N-formyl Peptide Receptor Activity Scavenger Receptor Binding Protein Binding RAGE Receptor Binding
	Biological Process	Immune Response Natural Killer Cell Mediated Cytotoxicity Regulation Of Immune Response	Activation Of MAPK Activity Complement Receptor Mediated Signaling Pathway Chemotaxis Inflammatory Response Signal Transduction G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-modulating G Protein-coupled Receptor Signaling Pathway Phospholipase C-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Cytosolic Calcium Ion Concentration Nitric Oxide Mediated Signal Transduction Cytokine-mediated Signaling Pathway Neutrophil Degranulation
Pathways		Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell	G alpha (i) signalling events Formyl peptide receptors bind formyl peptides and many other ligands Interleukin-10 signaling Neutrophil degranulation
Drugs			Nedocromil
Diseases
GWAS		Lymphocyte counts ( 32888494) Monocyte count ( 32888494) Ulcerative colitis ( 28067908)	Alopecia areata ( 25608926) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Eosinophil counts ( 32888494) Eosinophil percentage of white cells ( 32888494) Lymphocyte counts ( 32888494) Monocyte count ( 32888494) Neutrophil percentage of granulocytes ( 27863252) Neutrophil percentage of white cells ( 32888494) Tourette syndrome ( 30818990)
Interacting Genes		6 interacting genes: BMP10 CDK3 HLA-B RPS6KB1 SMCO4 THSD7B	5 interacting genes: ACTG1 ANXA1 GNAI2 GRK2 SAA1
Entrez ID		3811	2357
HPRD ID		09226	00646
Ensembl ID		ENSG00000167633	ENSG00000171051
Uniprot IDs		P43629 Q5UCE2 Q6H2G3 Q8N6C9	P21462
PDB IDs		3VH8 3WUW 5B38 5B39 5T6Z 5T70 6V3J
Enriched GO Terms of Interacting Partners?
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