ITIH1 and RBM15B

Data Source:
BioGRID (affinity chromatography technology)

		ITIH1	RBM15B
Description		inter-alpha-trypsin inhibitor heavy chain 1	RNA binding motif protein 15B
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Collagen-containing Extracellular Matrix Extracellular Exosome Blood Microparticle	Nucleus Nuclear Envelope Nucleoplasm Nucleolus Nuclear Speck RNA N6-methyladenosine Methyltransferase Complex
	Molecular Function	Serine-type Endopeptidase Inhibitor Activity Calcium Ion Binding	Nucleic Acid Binding RNA Binding Protein Binding
	Biological Process	Negative Regulation Of Endopeptidase Activity Hyaluronan Metabolic Process	Regulation Of Alternative MRNA Splicing, Via Spliceosome MRNA Splicing, Via Spliceosome RNA Methylation MRNA Export From Nucleus Nucleocytoplasmic Transport Dosage Compensation By Inactivation Of X Chromosome Viral Process Negative Regulation Of Transcription, DNA-templated
Pathways
Drugs		Zinc Zinc acetate Zinc chloride Zinc sulfate, unspecified form
Diseases
GWAS		Autism spectrum disorder or schizophrenia ( 28540026) Bipolar disorder ( 21926972 19416921 31043756) Blood protein levels ( 29875488) Body mass index ( 25673413) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Cortical surface area (MOSTest) ( 32665545) General cognitive ability ( 29844566) Glaucoma (primary open-angle) ( 25173105) Osteoarthritis (hip) ( 30374069) Pulse pressure ( 30578418) Schizophrenia ( 25056061 29483656 23974872) Schizophrenia, schizoaffective disorder or bipolar disorder ( 24166486) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545) Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction) ( 28448500) Waist circumference adjusted for BMI in active individuals ( 28448500) Waist circumference adjusted for body mass index ( 28448500) Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction) ( 28448500) Waist-to-hip ratio adjusted for body mass index ( 28448500)	Allergic disease (asthma, hay fever or eczema) ( 29679657)
Interacting Genes		2 interacting genes: PIK3CA SOX4	10 interacting genes: ATP6V0D2 CDC23 DVL3 EGR2 ERBB2 NAV2 NXF1 SRPK2 TNNC1 TRIM54
Entrez ID		3697	29890
HPRD ID		00927	11486
Ensembl ID		ENSG00000055957	ENSG00000259956
Uniprot IDs		B7Z8B6 P19827	Q8NDT2
PDB IDs		6FPY 6FPZ
Enriched GO Terms of Interacting Partners?
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