INPP5A and TUBGCP2

Data Source:
BioGRID (biochemical)

		INPP5A	TUBGCP2
Description		inositol polyphosphate-5-phosphatase A	tubulin gamma complex associated protein 2
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Membrane Dendrite	Spindle Pole Equatorial Microtubule Organizing Center Gamma-tubulin Complex Nucleoplasm Centrosome Microtubule Organizing Center Cytosol Cytoplasmic Microtubule Gamma-tubulin Small Complex Membrane
	Molecular Function	Inositol-polyphosphate 5-phosphatase Activity Protein Binding PH Domain Binding Inositol-1,4,5-trisphosphate 5-phosphatase Activity Inositol-1,3,4,5-tetrakisphosphate 5-phosphatase Activity	Protein Binding Gamma-tubulin Binding Microtubule Minus-end Binding
	Biological Process	Inositol Phosphate Metabolic Process Inositol Phosphate Dephosphorylation Phosphatidylinositol Dephosphorylation Inositol Phosphate-mediated Signaling Negative Regulation Of Neuron Death	Mitotic Cell Cycle Neuron Migration Microtubule Nucleation Brain Development Cytoplasmic Microtubule Organization Spindle Assembly Meiotic Cell Cycle Protein-containing Complex Assembly
Pathways		Synthesis of IP2, IP, and Ins in the cytosol	Recruitment of mitotic centrosome proteins and complexes Recruitment of NuMA to mitotic centrosomes
Drugs
Diseases
GWAS		Gait speed in old age ( 28077804) Heel bone mineral density ( 30598549 28869591) Migraine ( 27182965) Primary sclerosing cholangitis ( 27992413) Pulse pressure ( 30578418) Systolic blood pressure ( 30224653 30578418) Triglyceride levels ( 32203549) Triglyceride levels x short total sleep time interaction (2df test) ( 31719535) Triglycerides ( 30275531)	Mild influenza (H1N1) infection ( 26379185) Nonunion in individuals with fractures ( 30680360)
Interacting Genes		3 interacting genes: PLEK TEAD2 YWHAZ	3 interacting genes: KIF14 PCNT UBC
Entrez ID		3632	10844
HPRD ID		02521	18245
Ensembl ID		ENSG00000068383	ENSG00000130640
Uniprot IDs		Q14642	Q53EQ3 Q9BSJ2
PDB IDs			6V6B 6V6S 6X0V
Enriched GO Terms of Interacting Partners?
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