IDO1 and RBPMS

Data Source:
BioGRID (biochemical)

		IDO1	RBPMS
Description		indoleamine 2,3-dioxygenase 1	RNA binding protein, mRNA processing factor
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GO Annotations	Cellular Component	Cytoplasm Cytosol Smooth Muscle Contractile Fiber Stereocilium Bundle	P-body Nucleoplasm Cytosol Cytoplasmic Stress Granule
	Molecular Function	Tryptophan 2,3-dioxygenase Activity Electron Transfer Activity Heme Binding Indoleamine 2,3-dioxygenase Activity Metal Ion Binding	Transcription Coactivator Activity RNA Binding MRNA Binding Protein Binding Poly(A) Binding Protein Homodimerization Activity
	Biological Process	Immune System Process Positive Regulation Of T Cell Tolerance Induction Positive Regulation Of Chronic Inflammatory Response Positive Regulation Of Type 2 Immune Response Tryptophan Catabolic Process Inflammatory Response Female Pregnancy Tryptophan Catabolic Process To Kynurenine Electron Transport Chain Response To Lipopolysaccharide Negative Regulation Of Interleukin-10 Production Positive Regulation Of Interleukin-12 Production Multicellular Organismal Response To Stress Kynurenic Acid Biosynthetic Process 'de Novo' NAD Biosynthetic Process From Tryptophan Swimming Behavior Negative Regulation Of T Cell Proliferation Regulation Of Activated T Cell Proliferation Negative Regulation Of T Cell Apoptotic Process Positive Regulation Of T Cell Apoptotic Process	RNA Processing Response To Oxidative Stress Positive Regulation Of Pathway-restricted SMAD Protein Phosphorylation Positive Regulation Of Transcription, DNA-templated Positive Regulation Of SMAD Protein Signal Transduction
Pathways		Tryptophan catabolism
Drugs		Nitric Oxide Cannabidiol Medical Cannabis Nabiximols
Diseases
GWAS		Blood metabolite levels ( 24816252) Blood protein levels ( 29875488)	Blood urea nitrogen levels ( 31152163) Breast size ( 27182965) Eosinophil counts ( 32888494) Granulocyte count ( 27863252) Heart rate variability traits ( 22174390) Lymphocyte percentage of white cells ( 32888494 27863252) Mean corpuscular hemoglobin ( 32888494 27863252 28017375) Mean corpuscular volume ( 29403010 32888494 27863252 28017375) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Mosaic loss of chromosome Y (Y chromosome dosage) ( 28346444 31624269) Myeloid white cell count ( 27863252) Neutrophil count ( 32888494 27863252) Neutrophil percentage of white cells ( 32888494) Platelet count ( 32888494 27863252) Plateletcrit ( 32888494 27863252) PR interval ( 32439900) Sum basophil neutrophil counts ( 27863252) Sum neutrophil eosinophil counts ( 27863252) Systolic blood pressure ( 30224653) Total grey matter volume ( 31530798) White blood cell count ( 32888494)
Interacting Genes		5 interacting genes: APP DDX24 FBXL17 PPP1R16A TERF2IP	262 interacting genes: ABCF3 ADAM15 AMMECR1 ANAPC11 ANKMY1 APLN ARHGAP9 ARHGEF39 ARID5A ATN1 ATP6V0D1 ATP6V0E2 ATXN1 ATXN7L2 BANP BBS2 BCL6B BHLHE40 BOLL C10orf55 C11orf87 C19orf54 C1orf94 C20orf85 C22orf39 C9orf24 CAMK2A CAMK2B CCDC120 CCER1 CCNG1 CCNK CDC23 CDC42EP1 CDK6 CHCHD7 CLPP CNNM3 COL8A1 CRBN CREB5 CRX CRYBA1 CSN3 CSNK1G2-AS1 CYBA DAZAP2 DCAF8 DCDC2B DCTN5 DMRT3 DMRTB1 DOK3 DOK6 DPYSL4 DTX2 DVL2 EAF2 EFEMP2 ENKD1 EWSR1 EXOSC1 EYA2 FAM124B FAM166B FAM168A FASTK FBF1 FBXL18 FNDC11 FOXC2 FOXP3 FOXS1 FRG1 FXR2 GATA1 GATA2 GATAD2B GCM2 GLIS2 GLYCTK GPATCH2L GPS2 GRAP GRAP2 GSE1 HCK HEY2 HEYL HIVEP1 HNRNPLL HOXA1 HOXA9 HOXB9 HOXC8 HSFY1 IGF2 ILF3 INCA1 INIP IP6K2 KCTD9 KIF1A KIR2DL4 KLHDC7B KPNA2 KRAS KRTAP11-1 KRTAP12-1 KRTAP12-2 KRTAP12-4 KRTAP13-1 KRTAP13-3 KRTAP15-1 KRTAP19-1 KRTAP19-3 KRTAP19-5 KRTAP19-7 KRTAP23-1 KRTAP26-1 KRTAP3-1 KRTAP8-1 LASP1 LGALS9C LINC00482 LINC00588 LINC00908 LINC01547 LINC01588 LINC01869 LMO4 LONRF1 LRRC41 LZTS2 MAGED1 MCM5 MCM7 MEIS2 MGAT5B MKRN3 MLLT10 MORN3 MRPL20-AS1 MSX1 MVP MYH7B MYOZ2 NAB2 NANOG NAPRT NEDD9 NEU4 NKX2-5 NR1D2 NTAQ1 NYNRIN OTX1 PATZ1 PDLIM4 PER1 PGLS PHF1 PICALM PIH1D1 PIN1 PITX1 PITX2 PLAC8 PLSCR4 POGZ POLR3GL POM121 POU4F2 POU6F2 PPP1R16B PRKAA1 PRKAA2 PRKAB2 PRR20A PRR20B PRR20C PRR20D PRR20E PRR35 PSG11 PSMF1 QKI R3HDM2 RABL6 RAD54L2 RAMAC RBFOX1 RBFOX2 RBM24 RBM46 RBPMS2 RDH12 RHOBTB3 RHOXF2 RIPPLY1 ROR2 RPP25 RTP5 RUSC1 SBF2 SEMA4G SERF2 SF1 SFI1 SH3RF2 SIRPB1 SLC25A48 SMAD3 SMAP1 SMUG1 SNHG29 SNRPB SNRPC SPATA46 SPATA8 SPG7 STRBP TBX6 TCEA2 TCF7L2 TEKT5 TENT2 TEX37 TFG TIE1 TINAGL1 TLE5 TMEM42 TMSB4X TNS2 TOLLIP TOR1AIP2 TRAF4 TRIP13 TSC1 TSG101 TSGA10IP TSPYL6 TTLL10 TUSC2 UBAP2 VENTX VEZF1 VGLL3 VHL VHLL VPS37C WDR54 WDR90 YPEL3 ZBTB32 ZC3H10 ZIC1 ZNF34 ZNF385C ZNF488 ZNF581
Entrez ID		3620	11030
HPRD ID		00935	11870
Ensembl ID		ENSG00000131203	ENSG00000157110
Uniprot IDs		A0A348GSI3 P14902	B4E3T4 D3DSV0 Q93062
PDB IDs		2D0T 2D0U 4PK5 4PK6 4U72 4U74 5EK2 5EK3 5EK4 5ETW 5WHR 5WMU 5WMV 5WMW 5WMX 5WN8 5XE1 6AZU 6AZV 6AZW 6CXU 6CXV 6DPQ 6DPR 6E35 6E40 6E41 6E42 6E43 6E44 6E45 6E46 6F0A 6KOF 6KPS 6KW7 6MQ6 6O3I 6PU7 6PZ1 6R63 6TUE 6V52 6WJY	1BNY 5CYJ 5DET
Enriched GO Terms of Interacting Partners?
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