TNFRSF9 and SLC7A10

Data Source:
HPRD (in vitro)

		TNFRSF9	SLC7A10
Description		TNF receptor superfamily member 9	solute carrier family 7 member 10
Image			No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane External Side Of Plasma Membrane	Plasma Membrane Integral Component Of Plasma Membrane Membrane
	Molecular Function	Protein Binding Cytokine Binding Signaling Receptor Activity	Protein Binding Neutral Amino Acid Transmembrane Transporter Activity L-amino Acid Transmembrane Transporter Activity L-serine Transmembrane Transporter Activity
	Biological Process	Apoptotic Process Negative Regulation Of Cell Population Proliferation Tumor Necrosis Factor-mediated Signaling Pathway Regulation Of Cell Population Proliferation	Amino Acid Transmembrane Transport Amino Acid Transport Neutral Amino Acid Transport L-serine Transport D-alanine Transport D-serine Transport Leukocyte Migration L-alpha-amino Acid Transmembrane Transport
Pathways		TNFs bind their physiological receptors	Basigin interactions Amino acid transport across the plasma membrane
Drugs		Urelumab
Diseases
GWAS		Blond vs. brown/black hair color ( 30531825) Celiac disease ( 20190752) Crohn's disease ( 28067908) Inflammatory bowel disease ( 28067908 23128233) Psoriasis ( 25903422 23143594) Rheumatoid arthritis ( 30423114 24390342) Ulcerative colitis ( 28067908 21297633) Waist-hip ratio ( 28552196)	Allergic disease (asthma, hay fever or eczema) ( 29083406 29785011) Allergic rhinitis ( 30013184) Asthma ( 31361310 31959851 30929738 32296059 31619474) Asthma (adult onset) ( 30929738) Asthma (childhood onset) ( 30929738) Asthma or allergic disease (pleiotropy) ( 29785011) Eosinophil counts ( 32888494) Medication use (adrenergics, inhalants) ( 31015401) Medication use (glucocorticoids) ( 31015401) Multiple sclerosis ( 31604244) Red blood cell count ( 29403010) Triglyceride levels ( 32203549) Visceral adipose tissue adjusted for BMI ( 22589738) Visceral adipose tissue/subcutaneous adipose tissue ratio ( 22589738) White blood cell count (basophil) ( 29403010)
Interacting Genes		7 interacting genes: LRR1 SERP1 TNFRSF4 TNFSF9 TRAF1 TRAF2 TRAF3	2 interacting genes: APPBP2 SLC3A2
Entrez ID		3604	56301
HPRD ID		03767	12137
Ensembl ID		ENSG00000049249	ENSG00000130876
Uniprot IDs		Q07011	Q9NS82
PDB IDs		6A3V 6A3W 6BWV 6CPR 6CU0 6MGP 6MHR 6MI2
Enriched GO Terms of Interacting Partners?
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