ZC3H12D and SYNE1

Data Source:
BioGRID (affinity chromatography technology)

		ZC3H12D	SYNE1
Description		zinc finger CCCH-type containing 12D	spectrin repeat containing nuclear envelope protein 1
Image		No pdb structure
GO Annotations	Cellular Component	P-body Nucleus Nucleoplasm Cytoplasmic Ribonucleoprotein Granule	P-body Nucleus Nuclear Envelope Nuclear Outer Membrane Nucleoplasm Nucleolus Cytoplasm Golgi Apparatus Cytoskeleton Integral Component Of Membrane Sarcomere Nuclear Membrane Meiotic Nuclear Membrane Microtubule Tethering Complex Postsynaptic Membrane
	Molecular Function	MRNA Binding Endoribonuclease Activity Protein Binding Metal Ion Binding	RNA Binding Actin Binding Protein Binding Lamin Binding Enzyme Binding Protein Homodimerization Activity Actin Filament Binding Cytoskeleton-nuclear Membrane Anchor Activity
	Biological Process	MRNA Catabolic Process 3'-UTR-mediated MRNA Destabilization RNA Phosphodiester Bond Hydrolysis, Endonucleolytic	Nucleus Organization Golgi Organization Spermatogenesis Muscle Cell Differentiation Nuclear Matrix Anchoring At Nuclear Membrane
Pathways			Meiotic synapsis
Drugs
Diseases			Emery-Dreifuss muscular dystrophy Spinocerebellar ataxia (SCA); Machado-Joseph disease (SCA3)
GWAS		Asthma ( 32296059) Dupuytren's disease ( 28886342 21732829) Eosinophil counts ( 32888494) Eosinophil percentage of white cells ( 32888494)	Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined) ( 23453885) Bipolar disorder ( 28115744 21926972 31043756 28072414 20351715 21738484) Bipolar disorder or major depressive disorder ( 20351715) Bipolar I disorder ( 31043756) Body mass index ( 26426971) Endometriosis ( 28537267) Heel bone mineral density ( 30598549 28869591) Post bronchodilator FEV1 ( 26634245) Tonometry ( 17903302) Uterine fibroids ( 31249589 30194396 31649266)
Interacting Genes		1 interacting genes: ZC3H12A	21 interacting genes: ACTC1 APC BDKRB2 CAPN1 CDC42 CDC5L CEP63 DISC1 DTNBP1 ECPAS EMD LINC00839 LMNA MTDH MUSK MYOM1 NDEL1 SH3BP5 TNIK TP53RK USP21
Entrez ID		340152	23345
HPRD ID		19272	09762
Ensembl ID		ENSG00000178199	ENSG00000131018
Uniprot IDs		A2A288	A0A0C4DG40 B4E3R1 B7Z9Y6 F8WAI0 Q8NF91
PDB IDs			4DXR 6R15
Enriched GO Terms of Interacting Partners?
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