CLEC4D and LAG3

Data Source:
BioGRID (affinity chromatography technology, proximity labelling technology)

		CLEC4D	LAG3
Description		C-type lectin domain family 4 member D	lymphocyte activating 3
Image			No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Membrane Specific Granule Membrane Tertiary Granule Membrane Ficolin-1-rich Granule Membrane	Extracellular Region Plasma Membrane External Side Of Plasma Membrane Integral Component Of Membrane
	Molecular Function	Protein Binding Carbohydrate Binding Metal Ion Binding	Antigen Binding Transmembrane Signaling Receptor Activity Protein Binding MHC Class II Protein Binding
	Biological Process	Stimulatory C-type Lectin Receptor Signaling Pathway Adaptive Immune Response Positive Regulation Of Myeloid Dendritic Cell Activation Neutrophil Degranulation Innate Immune Response	Adaptive Immune Response Plasmacytoid Dendritic Cell Activation Cell Surface Receptor Signaling Pathway Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Negative Regulation Of Interleukin-2 Production Negative Regulation Of Regulatory T Cell Differentiation Positive Regulation Of Natural Killer Cell Mediated Cytotoxicity Regulation Of Immune Response
Pathways		Dectin-2 family Neutrophil degranulation	MHC class II antigen presentation
Drugs
Diseases
GWAS			Blood protein levels ( 30072576)
Interacting Genes		4 interacting genes: ACTN2 ANKRD46 JAGN1 ZDHHC22	2 interacting genes: CEBPZ CENPJ
Entrez ID		338339	3902
HPRD ID		13074	01077
Ensembl ID		ENSG00000166527	ENSG00000089692
Uniprot IDs		Q8WXI8	P18627
PDB IDs		2LS8 3WHD
Enriched GO Terms of Interacting Partners?
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