BIRC5 and AANAT

Data Source:
BioGRID (two hybrid)

		BIRC5	AANAT
Description		baculoviral IAP repeat containing 5	aralkylamine N-acetyltransferase
Image			No pdb structure
GO Annotations	Cellular Component	Nuclear Chromosome Chromosome, Centromeric Region Condensed Chromosome Kinetochore Nucleus Nucleoplasm Cytoplasm Cytosol Spindle Microtubule Midbody Chromosome Passenger Complex	Cytoplasm Cytosol Perinuclear Region Of Cytoplasm
	Molecular Function	Protein Binding Microtubule Binding Enzyme Binding Small GTPase Binding Identical Protein Binding Cysteine-type Endopeptidase Inhibitor Activity Involved In Apoptotic Process Metal Ion Binding Chaperone Binding	Aralkylamine N-acetyltransferase Activity Arylamine N-acetyltransferase Activity Protein Binding 14-3-3 Protein Binding
	Biological Process	Protein Phosphorylation Apoptotic Process Chromosome Segregation Sensory Perception Of Sound Positive Regulation Of Cell Population Proliferation Cytokine-mediated Signaling Pathway Protein-containing Complex Localization Regulation Of Apoptotic Process Negative Regulation Of Apoptotic Process Negative Regulation Of Transcription, DNA-templated Cell Division Regulation Of Cell Cycle	N-terminal Protein Amino Acid Acetylation Circadian Rhythm Response To Light Stimulus Photoperiodism Response To Zinc Ion Melatonin Biosynthetic Process Response To Insulin Response To Cytokine Response To Prostaglandin E Indolalkylamine Biosynthetic Process Response To Copper Ion Response To Corticosterone Response To Calcium Ion Cellular Response To CAMP
Pathways		Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion SUMOylation of DNA replication proteins RHO GTPases Activate Formins Interleukin-4 and Interleukin-13 signaling TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain Mitotic Prometaphase Neddylation EML4 and NUDC in mitotic spindle formation	Serotonin and melatonin biosynthesis
Drugs		Reserpine Berberine LY2181308	CoA-S-trimethylene-acetyl-tryptamine CoA-s-acetyl tryptamine CoA-S-acetyl 5-bromotryptamine Cannabidiol Medical Cannabis Nabiximols
Diseases			Delayed sleep phase syndrome
GWAS		Blood trace element (Se levels) ( 23720494) Periodontitis (Mean PAL) ( 24024966)	High light scatter reticulocyte count ( 32888494 27863252) High light scatter reticulocyte percentage of red cells ( 32888494 27863252) Immature fraction of reticulocytes ( 32888494) Mean corpuscular hemoglobin ( 32888494) Mean reticulocyte volume ( 32888494)
Interacting Genes		25 interacting genes: AURKA AURKB AURKC BIRC2 BIRC3 BIRC6 CASP3 CASP7 CASP9 CCDC85B CDCA8 CDK1 CDK4 DIABLO EVI5 FBXL7 H3-4 H3C14 HSP90AA1 INCENP KCNJ6 RAN RASA1 XIAP XPO1	8 interacting genes: BHLHE40 EIF4E3 F2 GRB10 KRTAP8-1 MDFI PRKACA YWHAZ
Entrez ID		332	15
HPRD ID		04520	02974
Ensembl ID		ENSG00000089685	ENSG00000129673
Uniprot IDs		A0A0B4J1S3 H3BLT4 O15392	F1T0I5 Q16613
PDB IDs		1E31 1F3H 1XOX 2QFA 2RAW 2RAX 3UEC 3UED 3UEE 3UEF 3UEG 3UEH 3UEI 3UIG 3UIH 3UII 3UIJ 3UIK 4A0I 4A0J 4A0N 6SHO 6YIE 6YIF 6YIH
Enriched GO Terms of Interacting Partners?
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