HLF and ABCC3

Data Source:
BioGRID (affinity chromatography technology)

		HLF	ABCC3
Description		HLF transcription factor, PAR bZIP family member	ATP binding cassette subfamily C member 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm	Plasma Membrane Membrane Integral Component Of Membrane
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding Double-stranded DNA Binding Sequence-specific DNA Binding Sequence-specific Double-stranded DNA Binding	ATP Binding ABC-type Xenobiotic Transporter Activity Glucuronoside Transmembrane Transporter Activity ABC-type Glutathione S-conjugate Transporter Activity ABC-type Bile Acid Transporter Activity ATPase Activity ATPase-coupled Transmembrane Transporter Activity Xenobiotic Transmembrane Transporter Activity Icosanoid Transmembrane Transporter Activity
	Biological Process	Regulation Of Transcription By RNA Polymerase II Multicellular Organism Development Skeletal Muscle Cell Differentiation Positive Regulation Of Transcription By RNA Polymerase II Rhythmic Process	Drug Transmembrane Transport Bile Acid And Bile Salt Transport Canalicular Bile Acid Transport Glucuronoside Transport Xenobiotic Transport Transmembrane Transport Leukotriene Transport Anion Transmembrane Transport Transport Across Blood-brain Barrier
Pathways			Recycling of bile acids and salts ABC-family proteins mediated transport
Drugs
Diseases
GWAS		Acute urticaria and angioedema (non-steroidal anti-inflammatory drug-induced) ( 24236485) Bipolar disorder ( 31043756) HDL cholesterol levels ( 32203549) Hematocrit ( 32888494) Hemoglobin ( 32888494) Metabolite levels ( 23823483) Night sleep phenotypes ( 27126917) Platelet distribution width ( 32888494) Red blood cell count ( 32888494) Serum uric acid levels ( 30993211) Urate levels ( 31985003 31578528 23263486) Urate levels in obese individuals ( 25811787) Waist circumference ( 28552196) Weight ( 28552196) Zinc levels ( 26025379)
Interacting Genes		6 interacting genes: ARNTL CREBBP DBP HNF4G MYB TET2	2 interacting genes: MLH1 MTDH
Entrez ID		3131	8714
HPRD ID		00797	06826
Ensembl ID		ENSG00000108924	ENSG00000108846
Uniprot IDs		Q16534	O15438 Q86VN9
PDB IDs
Enriched GO Terms of Interacting Partners?
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