GZMA and PCP4

Data Source:
BioGRID (biochemical)

		GZMA	PCP4
Description		granzyme A	Purkinje cell protein 4
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GO Annotations	Cellular Component	Immunological Synapse Extracellular Region Nucleus	Nucleus Cytoplasm Cytosol Protein-containing Complex
	Molecular Function	Serine-type Endopeptidase Activity Protein Binding Protein Homodimerization Activity	Calcium Ion Binding Protein Binding Calmodulin Binding
	Biological Process	Apoptotic Process Immune Response Response To Bacterium Cytolysis Negative Regulation Of Endodeoxyribonuclease Activity Positive Regulation Of Apoptotic Process Negative Regulation Of DNA Binding Negative Regulation Of Oxidoreductase Activity Proteolysis Involved In Cellular Protein Catabolic Process Pyroptosis Granzyme-mediated Programmed Cell Death Signaling Pathway Cytotoxic T Cell Pyroptotic Process	Positive Regulation Of Neuron Differentiation Calmodulin Dependent Kinase Signaling Pathway
Pathways
Drugs
Diseases
GWAS			Asthma ( 32296059) Metabolite levels ( 23823483) Systolic blood pressure (alcohol consumption interaction) ( 24376456) Venlafaxine response in generalised anxiety disorder (responders vs non-responders after 12 weeks) ( 28437668)
Interacting Genes		17 interacting genes: ACTG1 APEX1 GOLGA2 H1-1 H2BC21 HDC HMGB2 HNRNPK HSP90AA1 HSPA4 LMNA LMNB1 NCL NDUFS3 SET XRCC5 XRCC6	6 interacting genes: CALM1 CALML6 DAPK1 POT1 TERF1 TERF2IP
Entrez ID		3001	5121
HPRD ID		00771	03378
Ensembl ID		ENSG00000145649	ENSG00000183036
Uniprot IDs		P12544	P48539
PDB IDs		1HF1 1OP8 1ORF	2N77
Enriched GO Terms of Interacting Partners?
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