SNX24 and LOX

Data Source:
BioGRID (proximity labelling technology)

		SNX24	LOX
Description		sorting nexin 24	lysyl oxidase
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasmic Vesicle Membrane	Extracellular Region Collagen Trimer Extracellular Space Nucleus Extracellular Matrix
	Molecular Function	Protein Binding Phosphatidylinositol Phosphate Binding	Protein-lysine 6-oxidase Activity Copper Ion Binding Protein Binding Collagen Binding
	Biological Process	Protein Transport	Osteoblast Differentiation Regulation Of Protein Phosphorylation Cellular Protein Modification Process Heart Development Regulation Of Gene Expression Regulation Of Striated Muscle Tissue Development Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Peptidyl-lysine Oxidation Protein Phosphopantetheinylation Extracellular Matrix Organization Collagen Fibril Organization Bone Mineralization Lung Development Platelet-derived Growth Factor Receptor-beta Signaling Pathway Ascending Aorta Development Descending Aorta Development Wound Healing Response To Drug Regulation Of Apoptotic Process Protein Kinase B Signaling Regulation Of Megakaryocyte Differentiation Muscle Cell Cellular Homeostasis Elastic Fiber Assembly Blood Vessel Morphogenesis Response To Steroid Hormone Muscle Fiber Development Cell Chemotaxis Connective Tissue Development DNA Biosynthetic Process Regulation Of Receptor Binding Regulation Of Bone Development Cellular Response To Chemokine Regulation Of Platelet-derived Growth Factor Receptor-beta Signaling Pathway
Pathways			Elastic fibre formation Crosslinking of collagen fibrils
Drugs
Diseases
GWAS		Brain morphology (MOSTest) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Glucose homeostasis traits ( 25524916) HDL cholesterol levels ( 32203549) Mean platelet volume ( 32888494) Plateletcrit ( 27863252) Subcortical volume (MOSTest) ( 32665545)	Central corneal thickness ( 32528159) Coronary artery disease ( 28714974) Intraocular pressure ( 29617998) Lung function (FEV1/FVC) ( 30804560) Thiazide-induced adverse metabolic effects in hypertensive patients ( 23400010) Youthful appearance (self-reported) ( 32339537)
Interacting Genes		3 interacting genes: POU2F1 SH3GL3 YWHAZ	8 interacting genes: DHDDS DPT ELN H1-1 H1-5 H2BC11 H2BC21 RAF1
Entrez ID		28966	4015
HPRD ID		15413	01087
Ensembl ID		ENSG00000064652	ENSG00000113083
Uniprot IDs		Q9Y343	B0AZT2 B7ZAJ4 D0PNI2 P28300
PDB IDs		4AZ9
Enriched GO Terms of Interacting Partners?
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