DCAF4L1 and GNPDA2

Data Source:
BioGRID (proximity labelling technology)

		DCAF4L1	GNPDA2
Description		DDB1 and CUL4 associated factor 4 like 1	glucosamine-6-phosphate deaminase 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component		Nucleus Cytoplasm Cytosol
	Molecular Function		Glucosamine-6-phosphate Deaminase Activity Protein Binding Identical Protein Binding
	Biological Process		Carbohydrate Metabolic Process Glucosamine Catabolic Process N-acetylglucosamine Catabolic Process UDP-N-acetylglucosamine Biosynthetic Process N-acetylneuraminate Catabolic Process
Pathways			Glycolysis
Drugs
Diseases
GWAS		anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Depression ( 29700475) Helping behaviour (self reported) ( 29324852)	Adult body size ( 32376654) BMI (adjusted for smoking behaviour) ( 28443625) BMI at adiposity rebound ( 31840077) BMI in non-smokers ( 28443625) BMI in smokers ( 28443625) Body mass index ( 23563607 19079261 26961502 23669352 24861553 31453325 28892062 25673413 20935630 23583978 28448500) Body mass index (adult) ( 28430825) Body mass index (joint analysis main effects and physical activity interaction) ( 28448500) Body mass index (joint analysis main effects and smoking interaction) ( 28443625) Body mass index in physically active individuals ( 28448500) Body mass index in physically inactive individuals ( 28448500) Body mass index variance ( 31453325) Body size at age 10 ( 32376654) Childhood body mass index ( 33045005 26604143) General risk tolerance (MTAG) ( 30643258) Hand grip strength ( 29691431) Hip circumference ( 25673412) Menarche (age at onset) ( 25231870) Metabolite levels ( 23823483) Obese vs. thin ( 30677029) Obesity ( 23563607) Obesity (extreme) ( 30677029) Refractive error ( 32231278) Systolic blood pressure ( 26969751) Type 2 diabetes ( 30297969 32499647 30718926) Waist circumference ( 31453325 25673412) Waist circumference variance ( 31453325)
Interacting Genes			5 interacting genes: AMDHD2 ERRFI1 MAGOHB NTAQ1 TRIM27
Entrez ID		285429	132789
HPRD ID		18775	13594
Ensembl ID		ENSG00000182308	ENSG00000163281
Uniprot IDs		Q3SXM0	A0A024R9X5 Q8TDQ7
PDB IDs
Enriched GO Terms of Interacting Partners?
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