FBXL22 and NMB

Data Source:
BioGRID (affinity chromatography technology)

		FBXL22	NMB
Description		F-box and leucine rich repeat protein 22	neuromedin B
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleolus Cytosol SCF Ubiquitin Ligase Complex Z Disc	Extracellular Region Neuron Projection
	Molecular Function	Protein Binding Ubiquitin Protein Ligase Activity	Hormone Activity Neuropeptide Hormone Activity Protein Binding Neuromedin B Receptor Binding
	Biological Process	G2/M Transition Of Mitotic Cell Cycle Protein Polyubiquitination SCF-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process Entrainment Of Circadian Clock By Photoperiod Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Post-translational Protein Modification Regulation Of Cell Cycle	Signal Transduction G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Cytosolic Calcium Ion Concentration Neuropeptide Signaling Pathway Cell-cell Signaling Positive Regulation Of Cell Population Proliferation Glucose Homeostasis Positive Regulation Of Hormone Secretion Negative Regulation Of Hormone Secretion Arachidonic Acid Secretion
Pathways		Neddylation Antigen processing: Ubiquitination & Proteasome degradation	Peptide ligand-binding receptors G alpha (q) signalling events
Drugs
Diseases
GWAS		Chronic obstructive pulmonary disease or resting heart rate (pleiotropy) ( 30940143) Serum immune biomarker levels ( 32066700)	Autism spectrum disorder or schizophrenia ( 28540026) Bipolar disorder ( 31043756) Blood protein levels ( 30072576) Creatine kinase levels ( 29403010) P wave terminal force ( 28794112) Schizophrenia ( 29483656)
Interacting Genes		2 interacting genes: ACTN2 SKP1	4 interacting genes: BIRC2 GADD45G NMBR TPP1
Entrez ID		283807	4828
HPRD ID		16432	01210
Ensembl ID		ENSG00000197361	ENSG00000197696
Uniprot IDs		Q6P050	P08949
PDB IDs			1C98 1C9A
Enriched GO Terms of Interacting Partners?
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