IFNL1 and VPS26C

Data Source:
BioGRID (biochemical)

		IFNL1	VPS26C
Description		interferon lambda 1	VPS26 endosomal protein sorting factor C
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Interleukin-28 Receptor Complex	Nucleus Endosome
	Molecular Function	Signaling Receptor Binding Cytokine Activity Interleukin-28 Receptor Binding	Molecular_function Protein Binding
	Biological Process	Negative Regulation Of Type 2 Immune Response Receptor Signaling Pathway Via JAK-STAT Negative Regulation Of Cell Population Proliferation Cytokine-mediated Signaling Pathway Negative Regulation Of Interleukin-13 Production Negative Regulation Of Interleukin-5 Production Positive Regulation Of Interferon-gamma Production Positive Regulation Of Tyrosine Phosphorylation Of STAT Protein Negative Regulation Of Memory T Cell Differentiation Innate Immune Response Positive Regulation Of MHC Class I Biosynthetic Process Negative Regulation Of T Cell Differentiation Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Receptor Signaling Pathway Via JAK-STAT Positive Regulation Of Immune Response Defense Response To Virus	Intracellular Protein Transport Endocytic Recycling Retrograde Transport, Endosome To Plasma Membrane
Pathways		Other interleukin signaling Interleukin-20 family signaling
Drugs
Diseases
GWAS
Interacting Genes		1 interacting genes: IFNLR1	14 interacting genes: CBLB DECR2 INCA1 LRIF1 MAML3 MAPK6 MDM4 MEI4 MEOX2 PTPN21 RAB39B TEPSIN XPA ZNF655
Entrez ID		282618	10311
HPRD ID		09588	10390
Ensembl ID		ENSG00000182393	ENSG00000157538
Uniprot IDs		Q8IU54	A8MTY9 A8MY26 O14972
PDB IDs		3OG4 3OG6
Enriched GO Terms of Interacting Partners?
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