GPD2 and KCNJ3

Data Source:
BioGRID (biochemical)

		GPD2	KCNJ3
Description		glycerol-3-phosphate dehydrogenase 2	potassium inwardly rectifying channel subfamily J member 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Inner Membrane Glycerol-3-phosphate Dehydrogenase Complex	Plasma Membrane Voltage-gated Potassium Channel Complex External Side Of Plasma Membrane T-tubule Parallel Fiber To Purkinje Cell Synapse Integral Component Of Presynaptic Membrane
	Molecular Function	Glycerol-3-phosphate Dehydrogenase (quinone) Activity Calcium Ion Binding Sn-glycerol-3-phosphate:ubiquinone-8 Oxidoreductase Activity	Inward Rectifier Potassium Channel Activity Protein Binding G-protein Activated Inward Rectifier Potassium Channel Activity Voltage-gated Potassium Channel Activity Involved In Atrial Cardiac Muscle Cell Action Potential Repolarization Voltage-gated Potassium Channel Activity Involved In Ventricular Cardiac Muscle Cell Action Potential Repolarization
	Biological Process	Glycerol-3-phosphate Metabolic Process Glycerophosphate Shuttle Glycerol Catabolic Process	Potassium Ion Transport Regulation Of Ion Transmembrane Transport Response To Electrical Stimulus Regulation Of Heart Rate By Cardiac Conduction Membrane Repolarization During Atrial Cardiac Muscle Cell Action Potential Membrane Repolarization During Ventricular Cardiac Muscle Cell Action Potential Ventricular Cardiac Muscle Cell Membrane Repolarization Potassium Ion Import Across Plasma Membrane
Pathways		Synthesis of PA Triglyceride catabolism	Activation of G protein gated Potassium channels Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
Drugs			Atomoxetine Ethanol Halothane B-nonylglucoside Dronedarone Ifenprodil
Diseases
GWAS		Cognitive ability ( 29186694) Cognitive ability (MTAG) ( 29186694) Depression ( 29700475) Diisocyanate-induced asthma ( 25918132) Familial squamous cell lung carcinoma ( 29924316) General cognitive ability ( 29844566) Intelligence (MTAG) ( 29326435) Motion sickness ( 25628336) Myopia ( 27182965) Possible neuropathic pain in post total joint replacement surgery for osteoarthritis ( 28051079) Refractive error ( 32231278) Response to statin therapy ( 20339536) Spherical equivalent or myopia (age of diagnosis) ( 29808027) Ulcerative colitis ( 25082827) Urinary albumin-to-creatinine ratio ( 31630189)	Age at voice drop ( 27182965) Alcoholic chronic pancreatitis ( 28754779) Automobile speeding propensity ( 30643258) Dentures ( 31235808) Disease progression in age-related macular degeneration (adjusted for baseline) ( 29346644) Feeling miserable ( 29500382) General cognitive ability ( 29844566) Leisure-time exercise behaviour ( 30102679) Leisure-time exercise behaviour (age-stratified) ( 30102679) Lung function (FEV1/FVC) ( 30061609) Metabolite levels ( 23823483) Number of decayed, missing and filled tooth surfaces or use of dentures ( 31235808) Risk-taking tendency (4-domain principal component model) ( 30643258) Rosacea symptom severity ( 29771307) Smoking initiation ( 30617275) Smoking initiation (ever regular vs never regular) ( 30679032) Smoking status (ever vs never smokers) ( 30643258) Systemic lupus erythematosus ( 24871463)
Interacting Genes		1 interacting genes: ALDOA	4 interacting genes: GNB1 KCNJ5 KCNJ6 KCNJ9
Entrez ID		2820	3760
HPRD ID		00715	03323
Ensembl ID		ENSG00000115159	ENSG00000162989
Uniprot IDs		P43304 Q53T76	D2X9V0 D2XBF0 P48549
PDB IDs
Enriched GO Terms of Interacting Partners?
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