GOLGA3 and TCF7

Data Source:
BioGRID (affinity chromatography technology)

		GOLGA3	TCF7
Description		golgin A3	transcription factor 7
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Nucleoplasm Nucleolus Golgi Apparatus Cytosol Membrane Golgi Transport Complex Golgi Cisterna Membrane Extrinsic Component Of Golgi Membrane	Nucleus Nucleoplasm Nuclear Body Beta-catenin-TCF Complex
	Molecular Function	Protein Binding Cadherin Binding	Transcription Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity Protein Binding Beta-catenin Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Intra-Golgi Vesicle-mediated Transport Spermatogenesis	Regulation Of Transcription, DNA-templated Regulation Of Transcription By RNA Polymerase II Immune Response T Cell Receptor V(D)J Recombination Gamma-delta T Cell Differentiation Regulation Of Gamma-delta T Cell Differentiation Negative Regulation Of Transcription, DNA-templated Canonical Wnt Signaling Pathway Cellular Response To Interleukin-4 Beta-catenin-TCF Complex Assembly
Pathways			Formation of the beta-catenin:TCF transactivating complex Formation of the beta-catenin:TCF transactivating complex Deactivation of the beta-catenin transactivating complex Ca2+ pathway Binding of TCF/LEF:CTNNB1 to target gene promoters Repression of WNT target genes Repression of WNT target genes RUNX3 regulates WNT signaling
Drugs
Diseases
GWAS		Basal metabolic rate ( 31453325) Basal metabolic rate variance ( 31453325) Body mass index ( 28552196) Immune response to smallpox vaccine (IL-6) ( 22542470) Refractive error ( 32231278)	Autoimmune thyroid disease ( 32581359) Eosinophil counts ( 32888494) Eosinophil percentage of white cells ( 32888494) Medication use (thyroid preparations) ( 31015401) Menarche (age at onset) ( 25231870) Multiple sclerosis ( 31604244 24076602 21833088) Rheumatoid arthritis ( 32868391) Sum eosinophil basophil counts ( 27863252) Systemic lupus erythematosus ( 27399966 26502338 28714469) Vertical cup-disc ratio (multi-trait analysis) ( 31959993)
Interacting Genes		8 interacting genes: ATXN7 CASP2 CASP3 CASP7 GOLGA7 GOPC KCNJ1 TSNAX	2 interacting genes: SS18L1 UCHL5
Entrez ID		2802	6932
HPRD ID		03990	01797
Ensembl ID		ENSG00000090615	ENSG00000081059
Uniprot IDs		Q08378	B3KQ75 P36402
PDB IDs
Enriched GO Terms of Interacting Partners?
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