GMPR and FAM8A1

Data Source:
BioGRID (affinity chromatography technology)

		GMPR	FAM8A1
Description		guanosine monophosphate reductase	family with sequence similarity 8 member A1
Image			No pdb structure
GO Annotations	Cellular Component	Cytosol GMP Reductase Complex	Hrd1p Ubiquitin Ligase ERAD-L Complex Integral Component Of Membrane
	Molecular Function	GMP Reductase Activity Metal Ion Binding	Protein Binding
	Biological Process	Purine Nucleobase Metabolic Process Purine Nucleotide Metabolic Process Response To Cold Purine-containing Compound Salvage
Pathways		Purine salvage
Drugs		Guanosine-5'-Monophosphate
Diseases
GWAS		Blood metabolite levels ( 24816252) Gambling ( 22780124) General cognitive ability ( 29844566) Hemoglobin ( 32888494) Hemoglobin concentration ( 27863252) Hemoglobin levels ( 32327693) High light scatter reticulocyte count ( 32888494 27863252) High light scatter reticulocyte percentage of red cells ( 32888494 27863252) Immature fraction of reticulocytes ( 32888494) LDL cholesterol ( 20864672) Major depressive disorder ( 23377640) Mean corpuscular hemoglobin ( 29403010 32888494 27863252) Mean corpuscular hemoglobin concentration ( 29403010 32888494 27863252) Mean corpuscular volume ( 29403010 32888494 27863252) Mean spheric corpuscular volume ( 32888494) QT interval ( 24952745 29874175) Red blood cell count ( 32888494) Red cell distribution width ( 32888494) Response to statins (LDL cholesterol change) ( 22331829) Reticulocyte count ( 32888494 27863252) Reticulocyte fraction of red cells ( 32888494 27863252)	Idiopathic intracranial hypertension ( 29608535)
Interacting Genes			1 interacting genes: ATP13A2
Entrez ID		2766	51439
HPRD ID		00754	13316
Ensembl ID		ENSG00000137198	ENSG00000137414
Uniprot IDs		P36959	A0A024R006 Q9UBU6
PDB IDs		2BLE 2BWG
Enriched GO Terms of Interacting Partners?
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