DESI1 and CENPM

Data Source:
BioGRID (affinity chromatography technology)

		DESI1	CENPM
Description		desumoylating isopeptidase 1	centromere protein M
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GO Annotations	Cellular Component	Nucleus Cytosol Protein-containing Complex	Condensed Chromosome Kinetochore Nucleoplasm Cytosol
	Molecular Function	Protein Binding Identical Protein Binding Importin-alpha Family Protein Binding SUMO-specific Isopeptidase Activity
	Biological Process	Protein Export From Nucleus Protein Desumoylation Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Protein Modification By Small Protein Removal	CENP-A Containing Nucleosome Assembly
Pathways			Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion RHO GTPases Activate Formins Deposition of new CENPA-containing nucleosomes at the centromere Mitotic Prometaphase EML4 and NUDC in mitotic spindle formation
Drugs
Diseases
GWAS		General cognitive ability ( 29844566) Meat-related diet ( 32066663) Neuroticism ( 29255261) Refractive error ( 32231278)	Birth weight ( 23202124) Processed meat consumption ( 32066663) Refractive error ( 32231278) Schizophrenia ( 25056061 29483656)
Interacting Genes		33 interacting genes: ABI3 AGR3 CCDC158 CDIP1 CDSN CTAG1A CTAG1B CTAG2 DAZAP2 ERP29 EVI2B FGF7 GOLM1 KLRF1 MEOX2 NME3 NT5C3A PRR5 RNF4 RPS27A SHISA4 SHISA5 SMIM21 TAS2R41 UBA52 UBB UBC UBQLN1 UBQLN2 UBQLNL UHRF2 XPO1 ZBTB46	2 interacting genes: CENPS H3C1
Entrez ID		27351	79019
HPRD ID		18590	12798
Ensembl ID		ENSG00000100418	ENSG00000100162
Uniprot IDs		Q6ICB0	A0A024R1Q3 B1AHQ6 B1AHQ7 B1AHQ8 Q9NSP4
PDB IDs		3EBQ	4P0T 4WAU
Enriched GO Terms of Interacting Partners?
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