ERLEC1 and C2orf73

Data Source:
HPRD (in vitro, two hybrid)

		ERLEC1	C2orf73
Description		endoplasmic reticulum lectin 1	chromosome 2 open reading frame 73
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Lumen Endoplasmic Reticulum Quality Control Compartment
	Molecular Function	Protein Binding Unfolded Protein Binding
	Biological Process	ERAD Pathway Transmembrane Transport Negative Regulation Of Retrograde Protein Transport, ER To Cytosol
Pathways		ABC-family proteins mediated transport Hedgehog ligand biogenesis Hh mutants are degraded by ERAD Defective CFTR causes cystic fibrosis
Drugs
Diseases
GWAS		Blood protein levels ( 30072576 29875488) Diastolic blood pressure x smoking status (current vs non-current) interaction (1df test) ( 29455858) Diastolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858) High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Refractive error ( 32231278) Reticulocyte count ( 32888494) Reticulocyte fraction of red cells ( 32888494)	Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (min-P) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical thickness (MOSTest) ( 32665545) Estimated glomerular filtration rate ( 31015462 31451708 30604766) Estimated glomerular filtration rate in non-diabetics ( 31451708) Heel bone mineral density ( 30598549) Intraocular pressure ( 29617998) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545)
Interacting Genes		1 interacting genes: STK11	3 interacting genes: FCHSD2 HSPB1 SH3BP4
Entrez ID		27248	129852
HPRD ID		10310	13446
Ensembl ID		ENSG00000068912	ENSG00000177994
Uniprot IDs		Q96DZ1 V9HWD3	Q8N5S3
PDB IDs
Enriched GO Terms of Interacting Partners?
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