AMHR2 and TUBA1C

Data Source:
BioGRID (affinity chromatography technology)

		AMHR2	TUBA1C
Description		anti-Mullerian hormone receptor type 2	tubulin alpha 1c
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Receptor Complex Activin Receptor Complex	Nucleus Cytoplasm Microtubule Microtubule Cytoskeleton Vesicle
	Molecular Function	Protein Serine/threonine Kinase Activity Transforming Growth Factor Beta Receptor Activity, Type II Protein Binding ATP Binding Activin-activated Receptor Activity Hormone Binding Metal Ion Binding Activin Binding Anti-Mullerian Hormone Receptor Activity	GTPase Activity Structural Molecule Activity Structural Constituent Of Cytoskeleton Protein Binding GTP Binding
	Biological Process	Mullerian Duct Regression Protein Phosphorylation Transforming Growth Factor Beta Receptor Signaling Pathway Sex Differentiation Male Gonad Development Female Gonad Development BMP Signaling Pathway Activin Receptor Signaling Pathway Cellular Response To Growth Factor Stimulus Anti-Mullerian Hormone Signaling Pathway	Microtubule Cytoskeleton Organization Mitotic Cell Cycle Microtubule-based Process Cytoskeleton-dependent Intracellular Transport Cell Division
Pathways		Signaling by BMP	Translocation of SLC2A4 (GLUT4) to the plasma membrane Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane Gap junction assembly MHC class II antigen presentation Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion HSP90 chaperone cycle for steroid hormone receptors (SHR) Recruitment of NuMA to mitotic centrosomes Prefoldin mediated transfer of substrate to CCT/TriC Formation of tubulin folding intermediates by CCT/TriC Post-chaperonin tubulin folding pathway Recycling pathway of L1 Recycling pathway of L1 Hedgehog 'off' state Cilium Assembly Intraflagellar transport RHO GTPases activate IQGAPs RHO GTPases Activate Formins COPI-mediated anterograde transport COPI-dependent Golgi-to-ER retrograde traffic COPI-independent Golgi-to-ER retrograde traffic Mitotic Prometaphase The role of GTSE1 in G2/M progression after G2 checkpoint Carboxyterminal post-translational modifications of tubulin Carboxyterminal post-translational modifications of tubulin HCMV Early Events Assembly and cell surface presentation of NMDA receptors Activation of AMPK downstream of NMDARs Aggrephagy Aggrephagy EML4 and NUDC in mitotic spindle formation Sealing of the nuclear envelope (NE) by ESCRT-III Kinesins
Drugs		ATP	Epothilone D Patupilone CYT997 2-MERCAPTO-N-[1,2,3,10-TETRAMETHOXY-9-OXO-5,6,7,9-TETRAHYDRO-BENZO[A]HEPTALEN-7-YL]ACETAMIDE
Diseases		46,XY disorders of sex development (Other), including: Persistent Mullerian duct syndrome; Hypospadias; Cryptorchidism
GWAS			Brain morphology (MOSTest) ( 32665545) Cancer (pleiotropy) ( 27197191) Mean corpuscular hemoglobin ( 32888494) Mean platelet volume ( 32888494) Platelet count ( 32888494) Platelet distribution width ( 32888494 27863252)
Interacting Genes		4 interacting genes: AMH BMPR1B MAL TGFBR1	6 interacting genes: CDKN2A CRK ESR1 SUMO2 SUMO4 VIM
Entrez ID		269	84790
HPRD ID		02978	06747
Ensembl ID		ENSG00000135409	ENSG00000167553
Uniprot IDs		Q16671	B7Z1K5 F5H5D3 Q9BQE3
PDB IDs
Enriched GO Terms of Interacting Partners?
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