TIMM10 and CNTF

Data Source:
BioGRID (genetic interference)

		TIMM10	CNTF
Description		translocase of inner mitochondrial membrane 10	ciliary neurotrophic factor
Image
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Inner Membrane TIM23 Mitochondrial Import Inner Membrane Translocase Complex Mitochondrial Intermembrane Space Mitochondrial Intermembrane Space Protein Transporter Complex	Extracellular Region Extracellular Space Cytoplasm Axon
	Molecular Function	Protein Binding Zinc Ion Binding Protein Homodimerization Activity Chaperone Binding Protein Transporter Activity	Cytokine Activity Ciliary Neurotrophic Factor Receptor Binding Interleukin-6 Receptor Binding Protein Binding Growth Factor Activity Protein-containing Complex Binding
	Biological Process	Protein Targeting To Mitochondrion Sensory Perception Of Sound Protein Insertion Into Mitochondrial Inner Membrane Chaperone-mediated Protein Transport	Signal Transduction Positive Regulation Of Cell Population Proliferation Positive Regulation Of Gene Expression Cytokine-mediated Signaling Pathway Positive Regulation Of Tyrosine Phosphorylation Of STAT Protein Negative Regulation Of Neuron Apoptotic Process Negative Regulation Of Photoreceptor Cell Differentiation Regulation Of Retinal Cell Programmed Cell Death Astrocyte Activation Muscle Organ Morphogenesis Neuron Development Positive Regulation Of Axon Regeneration Ciliary Neurotrophic Factor-mediated Signaling Pathway
Pathways		Mitochondrial protein import Mitochondrial protein import	IL-6-type cytokine receptor ligand interactions
Drugs
Diseases
GWAS		Worry too long after an embarrassing experience ( 29500382)	Diastolic blood pressure ( 27841878) Inflammatory bowel disease ( 23128233) Medication use (agents acting on the renin-angiotensin system) ( 31015401) Pulse pressure ( 27841878) Systolic blood pressure ( 27841878) Ulcerative colitis ( 28067908)
Interacting Genes		3 interacting genes: SIK1B TBC1D21 ZNF655	13 interacting genes: AK8 APOE CNTFR CYSRT1 IL6R IL6ST KRT31 KRT40 LIFR NDUFAB1 RDM1 TEPSIN TRIP6
Entrez ID		26519	1270
HPRD ID		03768	00347
Ensembl ID		ENSG00000134809	ENSG00000242689
Uniprot IDs		P62072	P26441
PDB IDs		2BSK 7CGP	1CNT
Enriched GO Terms of Interacting Partners?
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