FAM162A and PDIA5

Data Source:
BioGRID (affinity chromatography technology)

		FAM162A	PDIA5
Description		family with sequence similarity 162 member A	protein disulfide isomerase family A member 5
Image		No pdb structure
GO Annotations	Cellular Component	Mitochondrion Cytosol Integral Component Of Membrane	Endoplasmic Reticulum Lumen Endoplasmic Reticulum Membrane
	Molecular Function	Protein Binding	Protein Disulfide Isomerase Activity Protein Binding Peptide Disulfide Oxidoreductase Activity Oxidoreductase Activity
	Biological Process	Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Positive Regulation Of Apoptotic Process Neuron Apoptotic Process Cellular Response To Hypoxia Positive Regulation Of Release Of Cytochrome C From Mitochondria	Protein Folding Protein Phosphopantetheinylation IRE1-mediated Unfolded Protein Response
Pathways			XBP1(S) activates chaperone genes
Drugs
Diseases
GWAS		Diastolic blood pressure ( 27841878) Risky sexual behaviors (alcohol dependence interaction) ( 28990359)	Blood protein levels ( 29875488) Fibrinogen levels ( 28107422 26561523) Interleukin-17 levels ( 27989323) Mean platelet volume ( 32888494 27863252) Platelet count ( 22139419 32888494 27863252) Platelet distribution width ( 32888494 27863252) Plateletcrit ( 32888494 27863252)
Interacting Genes		1 interacting genes: HSP90AA1	5 interacting genes: KRTAP1-3 KRTAP10-3 KRTAP10-7 MDFI UBQLN4
Entrez ID		26355	10954
HPRD ID		06422	08334
Ensembl ID		ENSG00000114023	ENSG00000065485
Uniprot IDs		Q96A26 Q9H2P1	Q14554
PDB IDs			4I6X
Enriched GO Terms of Interacting Partners?
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