FBXO22 and SERPINB7

Data Source:
BioGRID (affinity chromatography technology)

		FBXO22	SERPINB7
Description		F-box protein 22	serpin family B member 7
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytosol Z Disc	Extracellular Space Cytoplasm
	Molecular Function	Ubiquitin-protein Transferase Activity Protein Binding	Serine-type Endopeptidase Inhibitor Activity
	Biological Process	Protein Polyubiquitination Cellular Protein Modification Process Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Post-translational Protein Modification Regulation Of Skeletal Muscle Fiber Development	Negative Regulation Of Endopeptidase Activity Positive Regulation Of Transforming Growth Factor Beta1 Production Positive Regulation Of Collagen Biosynthetic Process Positive Regulation Of Glomerular Mesangial Cell Proliferation Positive Regulation Of Platelet-derived Growth Factor Production
Pathways		Neddylation Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Creatinine levels ( 29403010) Urate levels in obese individuals ( 25811787)	Allergic disease (asthma, hay fever and/or eczema) (age of onset) ( 32603359) Allergic disease (asthma, hay fever and/or eczema) (multivariate analysis) ( 32603359) Asthma ( 31361310 30929738 32296059 31619474) Asthma (age of onset) ( 31036433) Asthma (childhood onset) ( 31036433 30929738) Asthma onset (childhood vs adult) ( 30929738) Food allergy ( 29051540) Hen's egg allergy ( 29051540) Systolic blood pressure ( 29208002)
Interacting Genes		1 interacting genes: SNAI1
Entrez ID		26263	8710
HPRD ID		16437	04524
Ensembl ID		ENSG00000167196	ENSG00000166396
Uniprot IDs		Q8NEZ5	A8K3Q8 O75635
PDB IDs
Enriched GO Terms of Interacting Partners?
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